An interventional study of The high intensity interval training and The study moderate continuous training in Depression, Anxiety and University Students, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 18 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-27.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
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Among 20 studies in Depression by Cairo University — 7 open to participants now, 7 under way, none of them phase 3. Depression · Cairo University.
Among the 20 studies in Depression by Cairo University, this one is the 4th largest by enrollment of the 17 interventional ones that give a count, is one of 4 that started in 2025, is one of 16 with no phase, and was the 14th registered.
8,582 studies on the registry are indexed under Depression; 1,723 are open to participants now.
Browse Depression studies →7 of the 20 studies in Depression by Cairo University are open now, in 1 country. Recruiting first, the newest first:
Cairo University · Sites in Egypt
Ages 18–60
Cairo University · Sites in Egypt
Ages 35–55
Cairo University · Sites in Egypt
Ages 30–60 · Healthy volunteers
Cairo University · Sites in Egypt
Ages 50–64 · Women only
Cairo University
Ages 13–18 · Women only
By country, each count listing its studies:
Of the 1,089 Depression studies recruiting now, 470 (43%) set no upper age limit and 519 (48%) stop at 75 or younger; 203 take children under 18; 311 take healthy volunteers.
This study: 18 Years to 25 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
20 studies; the count open now beside each. This study's row is marked.
First in 2019; this study’s year is marked. 4 started in 2025.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 84 is close to the median of 81 across 7,066 interventional studies indexed under Depression.
Median enrollment 50 across the 17 interventional studies, 85 across the 3 observational. Of the 9 that completed or were terminated, 1 (11%) have results posted.
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Cairo University is the lead sponsor of 4,941 studies on the registry; 1,457 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
3 of the studies in Depression by Cairo University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07452341Cairo UniversityEffect of Virtual Reality on Depression in Adolescent Females | 2027-01-01 |
| NCT07776145Cairo UniversityEffect of Probiotic on Cognitive Function | 2027-09 |
| NCT07600411Cairo UniversityBinge Eating, Depression and Anxiety Outcomes After Sleeve Gastrectomy Versus Gastric Bypass: A Cohort Study | 2027-09 |
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Among the 20 studies in Depression by Cairo University, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This study was done to investigate the impact of gender differences and exercise intensities on depression and anxiety symptoms among university students
Depression among university students is a growing concern due to factors such as separation from family, transition to a performance-based environment, financial stressors, and uncertainty about postgraduation. An estimated 71% of Egyptian university students have at least minor depression. Depression is associated with lower academic performance and can lead to substance abuse, chronic conditions, and premature mortality. Despite the availability of effective treatment, only one in five university students receives minimally adequate treatment. Physical exercise is suggested as an affordable, low-cost, non-pharmacological treatment for depression and anxiety. Exercise can effectively relieve anxiety symptoms, and a study will evaluate depression and anxiety symptoms based on gender and exercise intensity among university students.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
It will consist of 14 female students; they will be receiving high intensity interval training.
Other: The high intensity interval training
It will consist of 14 male students; they will be receiving high intensity interval training.
Other: The high intensity interval training
It will consist of 14 female students; they will be receiving moderate intensity continuous training
Other: The study moderate continuous training
It will consist of 14 male students; they will be receiving moderate intensity continuous training
Other: The study moderate continuous training
It will consist of 14 female students; they will remain sedentary for the six-weeks intervention period.
It will consist of 14 male students; they will remain sedentary for the six-weeks intervention period
The training program for students in groups 1 and 2 involves high intensity interval training exercises, conducted three times per week for six weeks. The sessions include a 10-minute warm-up at 40% Heart Rate Reserve, four high-intensity work periods at 85-95% Heart Rate Reserve, three low-intensity work periods at 60-70% Heart Rate Reserve, and a 5- 10 minute cool down at 30% Heart Rate Reserve.
All students in groups 3\&4 will receive moderate continuous training 3 times per week for 6 weeks. Each session 40 to 50 minutes included a 5 to 10 minute warm-up, fo followed by 30 minutes of moderate aerobic exercise (treadmill walking exercise) with constant intensity at 60% to 70% Heart Rate Reserve and 5 to 10 minutes cool-down
assessment of the severity of depressive symptoms
The Hamilton Rating Scale for Depression will be used to assess the severity of depressive symptoms in students across six groups. The 17-item version ranges from 0 to 54, with scores ranging from 0 to 24. Scores between 0 and 6 indicate no depression, while scores between 7 and 17 indicate mild, 18-24 indicate moderate, and 24+ over 24 indicate severe depression. A decrease in scores of at least 50% indicates response, and scores of 7 or less after treatment indicate remission. The 17-item version has adequate reliability and validity.
Time frame: at baseline and after 6 weeks
assessment of severity of perceived anxiety symptoms
The Hamilton Rating Scale for Anxiety is a tool used to assess the severity of perceived anxiety symptoms. It consists of 14 symptom-defined elements, scoring from 0 to 4 (severe). The score range is 0 to 56, with scores above 17/56 indicating mild anxiety, 25-30 indicating moderate anxiety, and \>30 indicating severe anxiety. It has good psychometric properties.
Time frame: at baseline and after 6 weeks
assessment of physical fitness
The Harvard Step Test is a physical fitness index that measures an individual's ability to recover from muscular work and perform muscular tasks. It is performed on a 33 cm bench at 30 steps per minute, with heart rate measured every two seconds. The test is valid for estimating the cardiorespiratory fitness of college students and can be divided into three categories: excellent, good, average, and poor. The physical efficiency index rating ranges from 96 to 115, with the highest rating being excellent for males and the lowest being poor. The test is a reliable tool for assessing physical fitness.
Time frame: at baseline and after 6 weeks
assessment of heart rate during exercise
A pulse oximeter will be used to continuously monitor heart rate during exercise, ensuring the target heart rate (THR) remains within the pre-calculated value. The heart rate will be measured and monitored for all participants using the Karvonen formula. The process involves cleaning the index finger, placing the pulse oximeter on the index, and keeping the pulse for at least a minute until the reading stabilizes.
Time frame: at baseline and after 6 weeks
Ran from Aug 2025 to primary completion in Jan 2026, 5 months.
Of 3,471 non-industry interventional studies with no phase under Depression, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 41. This study's 5 months is below that.
Counting every sponsor, half of 3,569 studies reached it within 21 months; a quarter within 9 and three quarters within 41.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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