An observational study in Serum Uric Acid, sponsored by Hepatopancreatobiliary Surgery Institute of Gansu Province. Recruiting at 1 site in China. Open to participants aged 18 Years to 85 Years. Per ClinicalTrials.gov, last updated 2025-12-19.
Sponsored by Hepatopancreatobiliary Surgery Institute of Gansu Province · Observational
This retrospective study aims to analyze the impact of postoperative changes in serum uric acid (SUA) levels on the prognosis of patients undergoing pancreatic cancer resection.
Serum uric acid is a risk factor for gallbladder cancer in men and has a strong effect on pancreatic cancer in women. It has also been shown that elevated intracellular serum uric acid can induce an inflammatory stress response, which may promote its transformation, while elevated extracellular serum uric acidy further stimulate tumor cell proliferation, migration, and survival, and promote the development of highly aggressive cancer. In this study, the changes of serum uric acid before and after surgery was used as a prognostic marker for the survival of pancreatic cancer patients.
3,896 studies on the registry are indexed under Pancreatic Neoplasms; 1,007 are open to participants now.
This study's planned enrollment of 168 is below the median of 200 across 740 observational studies indexed under Pancreatic Neoplasms.
Browse Pancreatic Neoplasms studies →Hepatopancreatobiliary Surgery Institute of Gansu Province is the lead sponsor of 44 studies on the registry; 8 are open to participants now.
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Radical pancreatic cancer resection patients
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The diagnosis was confirmed by looking at a sample under a microscope: tissue from a biopsy or surgery (histology), or cells from a fluid or needle sample (cytology).
Your pathology report is the document that shows this.
A biopsy takes a small piece of tissue to examine. “Archival tissue” is a sample already taken, for example at diagnosis, and kept by the hospital.
Whether a stored sample will do depends on when it was taken, how much there is and what the study needs. Ask whether the study accepts your stored sample or needs a new biopsy.
Histologically or cytologically confirmed
The diagnosis was confirmed by looking at a sample under a microscope: tissue from a biopsy or surgery (histology), or cells from a fluid or needle sample (cytology).
Your pathology report is the document that shows this.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Biopsy and archival tissue
A biopsy takes a small piece of tissue to examine. “Archival tissue” is a sample already taken, for example at diagnosis, and kept by the hospital.
Whether a stored sample will do depends on when it was taken, how much there is and what the study needs. Ask whether the study accepts your stored sample or needs a new biopsy.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The increase of after serum uric acid operation compared with that before operation is≥10% Normal levels serum uric acid are typically 178 to 360 μm (3 to 6.8 mg/dl).
Diagnostic Test: serum uric acid test
The increase of after serum uric acid operation compared with that before operation \< 10% Normal serum uric acid levels are typically 178 to 360 μm (3 to 6.8 mg/dl).
Diagnostic Test: serum uric acid test
Detect the serum uric acid in blood sample
Overall survival
Overall survival was defined as the time from diagnosis to death.
Time frame: 3-5 years
Recurrence-free survival
Recurrence-free survival is the length of time from either the date of diagnosis or the start of therapy for a disease to the date of the first loco-regional or systemic recurrence.
Time frame: 3-5 years
Cost of hospitalization
The cost of the first hospitalization from admission to discharge.
Time frame: 3 months
Length of hospital stay
The first day of hospitalization for the first admission to the last day of discharge.
Time frame: 3 months
Pancreatic fistula
Whether or not pancreatic-intestinal anastomotic leakage occurred at the time of the first hospitalization.
Time frame: 3 months
Biliary fistula
Whether or not a biliary-intestinal anastomotic leak occurred at the time of the first hospitalization.
Time frame: 3 months
Bleeding
Whether or not there was bleeding after the first inpatient surgery.
Time frame: 3 months
Abdominal cavity infection
Whether or not there was an abdominal infection after the first inpatient surgery.
Time frame: 3 months
Plan to share: No
Started Jul 2025 (actual). Primary completion is estimated for Dec 2026, 17 months after the start.
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Hepatopancreatobiliary Surgery Institute of Gansu Province