An interventional study of GLP-1 formula liquid drink and Placebo in Obesity and Prediabetes, sponsored by Chung Shan Medical University. Not yet recruiting at 1 site in Taiwan. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-07-28.
Sponsored by Chung Shan Medical University · Not applicable, Interventional, and Prevention
A clinical human dietary intervention trial was conducted to investigate the effects of GLP-1 FORMUL liquid supplementation in individuals with prediabetes or obesity, with a focus on improvements in glycemic and lipid parameters, body composition, and gut microbiota profiles.
This 12-week randomized, placebo-controlled clinical trial aims to evaluate the nutritional and metabolic effects of GLP-1 FORMULA liquid supplementation. A total of 100 adult participants will be recruited and randomly assigned to one of two groups: (1) placebo group (n = 50), and (2) GLP-1 FORMULA group (n = 50). Participants will consume one bottle (50 g) of either GLP-1 FORMULA or placebo 30 minutes prior to their first meal each day for 8 weeks, followed by a 4-week post-intervention observation period.
Throughout the study, participants will undergo nutritional assessments including body composition analysis, waist-to-hip ratio measurements, appetite rating scales, gastrointestinal symptom questionnaires, and the Patient Health Questionnaire. Additionally, oral glucose tolerance tests (OGTT), standard blood biochemistry analyses, and fecal sample collection will be conducted at designated time points to evaluate glycemic control, metabolic markers, and gut microbiota composition.
6,296 studies on the registry are indexed under Obesity; 1,695 are open to participants now.
This study's planned enrollment of 100 is above the median of 78 across 4,878 interventional studies indexed under Obesity.
Browse Obesity studies →Chung Shan Medical University is the lead sponsor of 124 studies on the registry; 26 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
GLP-1 formula liquid drink, 50 g/glass jar
Dietary Supplement: GLP-1 formula liquid drink
The placebo contained the same base ingredients as the GLP-1 FORMULA but without the active GLP-1 FORMULA component.
Dietary Supplement: Placebo
One glass jar (50 g) of the GLP-1 formula liquid drink was administered once daily, 30 minutes prior to the first meal of the day.
One glass jar (50 g) of the placebo liquid drink was administered once daily, 30 minutes prior to the first meal of the day.
Change from baseline in BMI at weeks 8 and 12
Assessment of changes in BMI at baseline, week 8, and week 12
Time frame: Week 0, 8 and 12
Change from baseline in blood glucose at weeks 8 and 12
Assessment of blood glucose changes at weeks 0, 8, and 12
Time frame: Week 0, 8 and 12
This study is not yet recruiting, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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Chung Shan Medical University