An interventional study of Use of a Balloon Guide Catheter and Use of a Conventional (non-balloon) Guide Catheter in Acute Ischemic Stroke AIS, sponsored by University of South Florida. Recruiting at 2 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-07-22.
Sponsored by University of South Florida · Not applicable, Interventional, and Other
The purpose of this clinical trial is to study the two main types of approaches used in stroke thrombectomy and to investigate if one approach is more effective than the other, as this is currently not known. This study will be conducted in adults who have been diagnosed with an acute ischemic stroke and who are undergoing a thrombectomy for the treatment of their stroke. The main questions it aims to answer are:
Participants will be asked to
2,593 studies on the registry are indexed under Ischemic Stroke; 931 are open to participants now.
This study's planned enrollment of 186 is above the median of 120 across 1,752 interventional studies indexed under Ischemic Stroke.
Browse Ischemic Stroke studies →University of South Florida is the lead sponsor of 333 studies on the registry; 63 are open to participants now.
Of its 17 completed or terminated interventional studies of FDA-regulated products, 4 (24%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Use of a balloon guide catheter in stroke thrombectomy.
Other: Use of a Balloon Guide Catheter
Use of conventional (non-balloon guide) catheter in stroke thrombectomy.
Other: Use of a Conventional (non-balloon) Guide Catheter
Use of a balloon guide catheter in stroke thrombectomy.
Use of a conventional (non-balloon) guide catheter in stroke thrombectomy.
TICI Grading Scale Score
Use of a mTICI grading scale to look at the degree to which the vessel has been opened during a mechanical thrombectomy.
Time frame: Participant duration is 90 days.
Procedural Outcomes
Metrics associated with a standard of care thrombectomy procedure, such as length of procedure, will be collected.
Time frame: Participant duration is 90 days.
Number of Participants with Treatment Related Adverse Effects
Collection of data related to clincial and safety outcomes such as presence of a bleed.
Time frame: Participant duration is 90 days.
Plan to share: No — IPD will not be shared with participants as both catheters are routinely used in acute ischemic stroke thrombectomy. The decision to use a balloon guide versus a conventional guide catheter is usually left to the discretion of the operator.
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University of South Florida