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CompletedNCT07037693Updated Jun 25, 2025

Prediction of Postoperative Outcomes After Rectal Resection by the Comprehensive Complication Index (CCI)

An observational study in Rectal Diseases, sponsored by Cantonal Hospital of St. Gallen. Completed at 1 site in Switzerland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-06-25.

Sponsored by Cantonal Hospital of St. Gallen · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
958
Ages
18 Years and older
Sex
All
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Study summary

Postoperative complications after rectal resection can worsen the short-term postoperative outcomes and the long-term survival. This study aims to compare the comprehensive complication index (CCI) and the commonly used Clavien-Dindo classification (CDC) in predicting postoperative outcomes after rectal resection.

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Conditions studied

  • Rectal Diseases

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In context

Rectal Diseases

87 studies on the registry are indexed under Rectal Diseases; 14 are open to participants now.

This study's enrollment of 958 is above the median of 223 across 26 observational studies indexed under Rectal Diseases.

Browse Rectal Diseases studies →

Lead sponsor

Cantonal Hospital of St. Gallen is the lead sponsor of 79 studies on the registry; 9 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

All patients with rectal resection at the Cantonal Hospital of St.Gallen between 2012 and June 2024.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • All patients with rectal resection at the Cantonal Hospital of St.Gallen between 2012 and June 2024.

Exclusion criteria

Exclusion Criteria:

  • Missing CCI data
  • Missing CDC data
  • Incomplete 30-day follow-up
  • Decline to have their information included in the scientific data analysis
  • Age under 18 years
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
958 participants (actual)
Patient registry
No

Groups and cohorts

  • CCI

    Diagnostic Test: Comprehensive complication index (CCI)

  • CDC

    Diagnostic Test: Clavien-Dindo-Classification (CDC)

Interventions

  • Diagnostic testComprehensive complication index (CCI)

    Comprehensive complication index (CCI)

  • Diagnostic testClavien-Dindo-Classification (CDC)

    Clavien-Dindo-Classification (CDC)

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What researchers measure

Primary outcomes

  1. Length of hospital stay

    The predictive ability of the comprehensive-complication index and the Clavien-Dindo classification regarding the length of hospital stay after rectal resection will be compared through an area under the curve (AUC) analysis.

    Time frame: Periprocedural

Secondary outcomes

  1. 30-day readmission rate

    The predictive ability of the comprehensive-complication index and the Clavien-Dindo classification regarding the 30-day readmission rate after rectal resection will be compared through an area under the curve (AUC) analysis.

    Time frame: 30 days

  2. 90-day mortality

    The predictive ability of the comprehensive-complication index and the Clavien-Dindo classification regarding the 90-day mortality after rectal resection will be compared through an area under the curve (AUC) analysis.

    Time frame: 90 days

  3. Overall survival

    The patients 5-year overall survival will be compared between patients with low comprehensive-complication index and high comprehensive-complication index. A high comprehensive-complication score was defined as a score above the median score of the patients with a Clavien-Dinco classification grad 3a complication.

    Time frame: 5 years

  4. Comprehensive measure

    Evaluation of the comprehensive measure of the comprehensive-complications index through analysis of the number and severity of all complications for patients with multiple complications. Comparison of the range of the comprehensice complications-index score in patients with the same Clavien-Dindo classification.

    Time frame: 30 days

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Study locations

1 site
  • HOCH Health Ostschweiz, Kantonsspital St.Gallen
    Sankt Gallen, St.Gallen 9000, Switzerland
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 25, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07037693
Lead sponsor
Cantonal Hospital of St. Gallen
Responsible party
Yanic Ammann (Principal Investigator, Cantonal Hospital of St. Gallen) — Principal investigator
First posted
Jun 25, 2025
Start date
Jan 1, 2012
Primary completion
Jun 30, 2024
Completion
Nov 30, 2024
Last update
Jun 25, 2025

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2025. You cannot join it, but the record below documents what was studied.

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