An interventional study of Negative pressure ventilation and positive pressure ventilation in Critical Illness, Heart Failure and LVAD, sponsored by Karlsburg Hospital. Recruiting at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-18.
Sponsored by Karlsburg Hospital · Not applicable, Interventional, and Treatment
All patients undergoing an implantation of a durable left ventricular assist device and monitored by pulmonary artery catheter showing no adverse events after surgery are included in the study and ventilated for 15 minutes using extra thoracic negative pressure ventilation and usual intrathoracic positive pressure ventilation. Hemodynamics changes between both ventilation modes, especially focussing on right ventricular function and measured by a pulmonary artery catheter, are compared.
1,881 studies on the registry are indexed under Critical Illness; 462 are open to participants now.
This study's planned enrollment of 30 is below the median of 90 across 979 interventional studies indexed under Critical Illness.
Browse Critical Illness studies →Karlsburg Hospital is the lead sponsor of 4 studies on the registry; 4 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Device: Negative pressure ventilation · Device: positive pressure ventilation
All participants are ventilated with negative pressure ventilation first
All participants are ventilated using positive pressure ventilation after negative pressure ventilation
RVSWI
right ventricular stroke work index
Time frame: one minute
Plan to share: Undecided
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Karlsburg Hospital