An observational study in Negative Pressure Ventilation, Right Ventricular Dysfunction and Right Ventricular Failure, sponsored by Karlsburg Hospital. Not yet recruiting at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-08-26.
Sponsored by Karlsburg Hospital · Observational
Patients receives induction of general anesthesia for interventional tricuspidal clipping and standard monitoring for this procedure including arterial and central venous line and transesophageal ultrasound. A cuirass for extrathoracal negative pressure ventilation is placed onto the chest but not switched on. During usual positive pressure ventilation a ventilatory, a hemodynamic and a 3D full volume ultrasounddataset of the right and left ventricle is recorded and severity of tricuspidal regurgitation examined. Afterwards negative pressure ventilation is started and positive pressure ventilation reduced as far as possible without reduction of tidal volumes. The same dataset of ventilation, hemodynamics and ultrasound is collected again during negative pressure ventilation. Afterwards the cuirass gets removed, study finished and everything proceeds as during standard procedure.
90 studies on the registry are indexed under Ventricular Dysfunction, Right; 28 are open to participants now.
This study's planned enrollment of 30 is below the median of 100 across 51 observational studies indexed under Ventricular Dysfunction, Right.
Browse Ventricular Dysfunction, Right studies →Karlsburg Hospital is the lead sponsor of 4 studies on the registry; 4 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All patients for tricuspidal clipping without an exclusion criterium
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Substitution of positive pressure ventilation by negative pressure ventilation
stroke volume index
transesophageal ultrasound measurement
Time frame: 1 minute
RVEF
transesophageal ultrasound measurement
Time frame: 1 minute
LVEF
transesophageal ultrasound measurement
Time frame: 1 minute
volumes of chambers
transesophageal ultrasound measurement
Time frame: 1 minute
strain
transesophageal ultrasound measurement
Time frame: 1 minute
VC
transesophageal ultrasound measurement
Time frame: 1 minute
PISA
transesophageal ultrasound measurement
Time frame: 1 minute
EROA
transesophageal ultrasound measurement
Time frame: 1 minute
area of regurgitation of tricuspid valve
transesophageal ultrasound measurement
Time frame: 1 minute
arterial blood pressures
hemodynamic measurements
Time frame: 1 minute
venous blood pressures
hemodynamic measurements
Time frame: 1 minute
pulmonal blood pressures
hemodynamic measurements
Time frame: 1 minute
heart frequency
hemodynamic measurements
Time frame: 1 minute
tidal volume
ventilatory measurements
Time frame: 1 minute
minute volume
ventilatory measurements
Time frame: 1 minute
breathing rate
ventilatory measurements
Time frame: 1 minute
etCO2
ventilatory measurements
Time frame: 1 minute
pO2 in the blood
blood gases
Time frame: 1 minute
pCO2 in the blood
blood gases
Time frame: 1 minute
Laktat
blood gases
Time frame: 1 minute
cerebral oximetry
NIRS
Time frame: 1 minute
Plan to share: No
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This study is not yet recruiting, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.
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Ventricular Dysfunction, Right →
Karlsburg Hospital