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RecruitingNCT07010783Updated Mar 24, 2026

Respiratory Functions in Parkinson's Disease

An observational study in Parkinson Disease, sponsored by Ankara University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 50 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-24.

Sponsored by Ankara University · Observational

From the registry’s dates

  • Primary completion was expected by Apr 2026, 6 months ago, but the record still lists the study as recruiting.
  • Started Jul 2025; still recruiting 1 year 3 months later.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
100
Ages
50 Years to 80 Years
Sex
All
01

Study summary

The aim is to examine respiratory functions, inspiratory muscle strength, respiratory function, physical fitness and aerobic capacity in Parkinson's disease patients. Individuals between the ages of 50-80 who have been diagnosed with Parkinson's disease by a neurologist and healthy individuals with similar demographic characteristics will be included in the study as a control group. In addition, patients will be divided into three groups as above and below 2.5 and healthy controls according to the Modified Hoehn and Yahr Scale. Demographic information of the individuals will be recorded and clinical evaluations will be made. The staging of Parkinson's patients will be done with the Modified Hoehn and Yahr Scale, and the severity of the disease will be done with the Unified Parkinson's Disease Rating Scale. The inspiratory muscle strength of the individuals will be evaluated with the PowerBreath K5, respiratory functions with the Pulmonary Function Test device, and physical fitness and aerobic capacity with the Senior Fitness Test.

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Conditions studied

  • Parkinson Disease

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03

In context

Parkinson Disease

4,487 studies on the registry are indexed under Parkinson Disease; 1,082 are open to participants now.

This study's planned enrollment of 100 is close to the median of 96 across 1,057 observational studies indexed under Parkinson Disease.

Browse Parkinson Disease studies →

Lead sponsor

Ankara University is the lead sponsor of 312 studies on the registry; 68 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients with Parkinson's disease who came to the neurology outpatient clinic for routine examination and who met the appropriate inclusion criteria and healthy individuals with similar demographic characteristics.

Inclusion criteria

  • Age 50 to 80
  • Mini Mental State Examination score of 24 to 30
  • Diagnosed with Parkinson's Disease by a neurologist

Exclusion criteria

Exclusion Criteria:

  • Sözlü iletişim kuramama
  • Yürüme yardımcısı kullanıma
  • Ciddi görme bozukluğu, ek nörolojik bozuklukları ve/veya konjestif kalp yetmezliği olan yaşlılar
  • Egzersiz yapılması tavsiye edilmeyen yaşlı yetişkinler.
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
100 participants (estimated)
Patient registry
No

Groups and cohorts

  • Early Stage Patients with Parkinson's Disease

    According to the Modified Hoehn and Yahr Scale (MHÖ), patients with a score below 2.5

  • Advanced Stage Patients with Parkinson's Disease

    According to the Modified Hoehn and Yahr Scale (MHÖ), patients with 2.5 and above

  • Control Group

    Healthy individuals with similar demographic characteristics

06

What researchers measure

Primary outcomes

  1. Inspiratory Muscle Strength Measurement

    In this study, the inspiratory muscle strength of the participants will be measured using the Power Breath device.

    Time frame: Baseline

  2. Unified Parkinson's Disease Rating Scale

    This scale will evaluate the severity and stage of the participants' Parkinson's disease.

    Time frame: Baseline

  3. Evaluation of Respiratory Functions

    Participants' respiratory functions will be evaluated using a standard respiratory function test device.

    Time frame: Baseline

  4. Senior Fitness Test

    The physical fitness levels of the participants will be evaluated using the Senior Fitness Test.

    Time frame: Baseline

07

Study locations

1 of 1 sites recruiting
08

References and documents

Publications

  • Shill H, Stacy M. Respiratory function in Parkinson's disease. Clin Neurosci. 1998;5(2):131-5. PubMed 10785839 ↗
  • Morris ME, Iansek R, Matyas TA, Summers JJ. Ability to modulate walking cadence remains intact in Parkinson's disease. J Neurol Neurosurg Psychiatry. 1994 Dec;57(12):1532-4. doi: 10.1136/jnnp.57.12.1532. PubMed 7798986 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 24, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07010783
Lead sponsor
Ankara University
Collaborators
Hacettepe University, Atılım University
Responsible party
Büşra Seçkinoğulları Korkusuz (Principal Investigator, Ankara University) — Principal investigator
First posted
Jun 8, 2025
Start date
Jul 1, 2025
Primary completion
Apr 2026 (estimated)
Completion
May 2026 (estimated)
Last update
Mar 24, 2026

Study contacts

Büşra Seçkinoğulları Korkusuz, PhD
Contact
bskorkusuz@ankara.edu.tr
+905442436914
Süleyman Korkusuz, PhD
study chair · Atılım University
Ayla Fil Balkan, Assoc Prof
study chair · Hacettepe University
Gül Yalçın Çakmaklı, Assoc Prof
study chair · Hacettepe University
Neslihan Durutürk, Prof.Dr
study chair · Baskent University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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