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Not yet recruitingNCT06958757Updated May 6, 2025

A Study on the Effectiveness of Ankle Dorsiflexion Range of Motion Training in Patients With Patellofemoral Joint Pain.

An interventional study of Standard Exercise Therapy + Ankle Dorsiflexion Training and Standard Exercise Therapy Only in Patellofemoral Pain, PFP, sponsored by Tianjin University of Sport. Not yet recruiting. Open to participants aged 18 Years to 30 Years. Per ClinicalTrials.gov, last updated 2025-05-06.

Sponsored by Tianjin University of Sport · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Sep 2025, 1 year ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
64
Allocation
Randomized
Ages
18 Years to 30 Years
Sex
All
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Study summary

Patellofemoral Pain (PFP) is a common knee condition causing pain around the kneecap during activities like running or squatting. Limited ankle flexibility ("dorsiflexion" - how far participants can lift their toes toward the shin) may worsen PFP by altering leg movements. This study investigates whether adding ankle flexibility exercises to standard knee-strengthening programs improves outcomes for young adults with PFP. Active adults aged 18-30 with PFP and limited ankle flexibility (measured with a simple tool) are eligible, excluding those with prior knee/ankle surgeries, fractures, or conditions like arthritis. Sixty-four participants will be randomly assigned to either an Exercise + Ankle Training group (standard knee exercises plus targeted ankle training) or an Exercise-Only group for 8 weeks under physiotherapist guidance. Outcomes include improvements in knee pain scores (Kujala Scale), ankle flexibility changes, and muscle coordination measured with non-invasive sensors. If effective, ankle flexibility training could provide a low-cost addition to current treatments, helping patients resume activities with less pain. The study follows international ethical guidelines and has received preliminary ethics approval (No. TJUS-2025-054).

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Conditions studied

  • Patellofemoral Pain, PFP
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In context

Patellofemoral Pain Syndrome

295 studies on the registry are indexed under Patellofemoral Pain Syndrome; 75 are open to participants now.

This study's planned enrollment of 64 is above the median of 45 across 242 interventional studies indexed under Patellofemoral Pain Syndrome.

Browse Patellofemoral Pain Syndrome studies →

Lead sponsor

Tianjin University of Sport is the lead sponsor of 4 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 30 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Aged 18-30 years
  • Diagnosed with patellofemoral pain (PFP) per clinical guidelines (anterior knee pain aggravated by ≥2 activities: running, squatting, stair climbing)
  • Ankle dorsiflexion range of motion (ROM) \<10° (measured via goniometer in weight-bearing)
  • BMI 18.5-28 kg/m²
  • Engage in regular physical activity (≥3 sessions/week)

Exclusion criteria

Exclusion Criteria:

  • Ankle fractures
  • Achilles tendon rupture
  • Rheumatoid arthritis
  • Gout, or systemic diseases
  • Prior knee/ankle surgeries
  • Concurrent lower limb injuries (e.g., ligament tears, meniscal pathology)
  • Neurological disorders affecting mobility
  • Participation in other lower limb rehabilitation programs within 3 months
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
64 participants (estimated)

Study arms

  • Experimental
    experimental group

    standard exercise + ankle dorsiflexion training

    Other: Standard Exercise Therapy + Ankle Dorsiflexion Training

  • Active comparator
    control group

    standard exercise only

    Other: Standard Exercise Therapy Only

Interventions

  • OtherStandard Exercise Therapy + Ankle Dorsiflexion Training

    The experimental group receives: Standard Exercise Therapy (30 min/session, 3x/week for 8 weeks): Quadriceps eccentric exercises (e.g., slow step-downs), Hip abductor strengthening (e.g., side-lying leg lifts), and Neuromuscular control drills (e.g., single-leg balance on unstable surfaces). Ankle Dorsiflexion Training (15 min/session, 3x/week for 8 weeks): Mobilization techniques (posterior glides of the talus), Resistance band exercises (dorsiflexion against elastic bands), Progressive Achilles tendon stretching (weight-bearing calf stretches). Exercise progression (resistance/intensity) is adjusted biweekly based on functional assessments.

  • OtherStandard Exercise Therapy Only

    Standard Exercise Therapy (30 min/session, 3x/week for 8 weeks): Quadriceps eccentric exercises (e.g., slow step-downs), Hip abductor strengthening (e.g., side-lying leg lifts), and Neuromuscular control drills (e.g., single-leg balance on unstable surfaces). Exercise progression (resistance/intensity) is adjusted biweekly based on functional assessments.

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What researchers measure

Primary outcomes

  1. Kujala Anterior Knee Pain Scale

    Time frame: Assess all outcome measures at baseline (pre-intervention) and immediately after the completion of the 8-week intervention program (post-intervention).

  2. Ankle dorsiflexion range of motion

    Time frame: Assess all outcome measures at baseline (pre-intervention) and immediately after the completion of the 8-week intervention program (post-intervention).

Secondary outcomes

  1. sEMG co-contraction ratios

    Time frame: All outcome measures (sEMG co-contraction) ratios are assessed at baseline (pre-intervention) and immediately after completing the 8-week intervention program (post-intervention).

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Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 6, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06958757
Lead sponsor
Tianjin University of Sport
Responsible party
Wu Yuan (Principal Investigator, Tianjin University of Sport) — Principal investigator
First posted
May 6, 2025
Start date
May 6, 2025 (estimated)
Primary completion
Sep 10, 2025 (estimated)
Completion
Sep 10, 2025 (estimated)
Last update
May 6, 2025

Study contacts

yuan wu
Contact
15750642556@163.com
+8615750642556

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.

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