An interventional study of Cognitive behavioral therapy and Cognitive rehabilitation in Concussion, Brain and Mild Traumatic Brain Injury, sponsored by University of British Columbia. Recruiting at 8 sites in Canada. Open to participants aged 18 Years to 59 Years. Per ClinicalTrials.gov, last updated 2026-06-02.
Sponsored by University of British Columbia · Not applicable, Interventional, and Treatment
Among 13 studies in Brain Concussion by University of British Columbia — 2 open to participants now, 3 under way, none of them phase 3. Brain Concussion · University of British Columbia.
Among the 13 studies in Brain Concussion by University of British Columbia, this one is the 3rd largest by planned enrollment, is the only one that started in 2025, is one of 12 with no phase, and was the 13th registered.
637 studies on the registry are indexed under Brain Concussion; 163 are open to participants now.
Browse Brain Concussion studies →2 of the 13 studies in Brain Concussion by University of British Columbia are open now, in 1 country. Recruiting first, the newest first:
University of British Columbia · Sites in Canada
By country, each count listing its studies:
Of the 112 Brain Concussion studies recruiting now, 33 (29%) set no upper age limit and 72 (64%) stop at 75 or younger; 24 take children under 18; 38 take healthy volunteers.
This study: 18 Years to 59 Years · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
13 studies; the count open now beside each. This study's row is marked.
First in 2009; this study’s year is marked. 1 started in 2025.
This study's planned enrollment of 184 is above the median of 63 across 446 interventional studies indexed under Brain Concussion.
Median enrollment 64 across the 13 interventional studies. Of the 6 that completed or were terminated, 0 (0%) have results posted.
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University of British Columbia is the lead sponsor of 1,339 studies on the registry; 259 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 1 (17%) have results posted.
None of the studies under way reaches primary completion within a year.
Among the 13 studies in Brain Concussion by University of British Columbia, from their registry updates:
Nothing recorded among them since 2026-09-25.
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Persistent memory symptoms after concussion are common, and likely perpetuated by unhelpful illness beliefs and coping behaviors. Results from a pilot study suggested that traditional cognitive rehabilitation and a novel cognitive-behavioral therapy (CBT) protocol were both associated with improvements in subjective memory functioning. The present study will more definitively compare the effectiveness of these interventions for improving subjective memory functioning after concussion.
The primary research aims of this study are to determine whether cognitive behavioral therapy (CBT) and cognitive compensatory strategy training (CCST) improves subjective memory functioning compared to usual care, and to compare the effectiveness of CBT and CCST. This study is a multisite three-armed randomized control trial (RCT) that will randomize adults with persistent memory symptoms following concussion to CBT, CCST, or a covert waitlist condition (2:2:1). Participants will be blinded to the other arms of the study and the study hypotheses.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Behavioral: Cognitive behavioral therapy
Behavioral: Cognitive rehabilitation
Cognitive behavioral therapy (CBT) is delivered by a psychologist over 10 individual (1:1) manualized videoconference sessions. The goal of this therapy is for participants to use their memory more normally (i.e., reduce avoidance and safety behaviors) and view memory lapses as less threatening.
Cognitive compensatory strategy training (CCST), a traditional cognitive rehabilitation intervention, is delivered by a Occupational Therapist over 10 individual (1:1) manualized videoconference sessions. Participants optimize their use of current compensatory strategies and/or learn new ones suited to their needs and lifestyle. The goal is to minimize memory lapses in daily life.
Multifactorial Memory Questionnaire-Satisfaction scale
Measures participants' concern, satisfaction, and overall appraisal of their memory ability. Participants rate their agreement with 18 statements. Total scores range from 0 to 72, with lower total scores indicating worse subjective memory functioning.
Time frame: Week 20
Fear-Avoidance of Memory Loss Scale
Assesses fears and avoidance behaviors associated with memory decline. Participants rate 24 items on a 5-point scale, where the higher scores indicate greater memory concern and maladaptive coping.
Time frame: Week 1 and week 20
Patient Global Impression of Change scale
Participants rate how much their memory functioning has improved or declined overall since the beginning of the study, on a single item rated on a 7-point scale where the midpoint is no change.
Time frame: Week 20
Work and Social Adjustment Scale
Participants rate how much their condition interferes with their ability to carry out occupational and social activities across 5 items, on a scale from 1-7 where higher scores indicate more difficulty.
Time frame: Week 1 and week 20
Not enrolling at this site.
Plan to share: No
Started Jul 2025 (actual). Primary completion is estimated for Apr 2028, 33 months after the start.
Of 248 non-industry interventional studies with no phase under Brain Concussion, half reached primary completion within 28 months of starting (the median), counting those still running; a quarter within 19 and three quarters within 47. This study's planned 33 months is above that.
Counting every sponsor, half of 264 studies reached it within 28 months; a quarter within 19 and three quarters within 47.
How these figures are worked out, and which studies are left out of them.
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