An interventional study of Sham-BFR and Blood Flow Restriction Training in Osteoarthritis (OA) of the Knee and Muscle Atrophy, sponsored by University Hospital, Bonn. Completed at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-04-24.
Sponsored by University Hospital, Bonn · Not applicable, Interventional, and Treatment
The present study investigates the effects of blood flow restriction training on muscular recovery during out-patient rehabilitation after elective total knee arthroplasty
The present study evaluated the impact of blood flow restriction training in the context of three-week outpatient rehabilitation following TKA, in accordance with the guidelines of the German Pension Insurance System. The in-rehabilitation and post-rehabilitation muscle status, strength, knee functionality, impairments in daily life and subjective pain perception were measured.
494 studies on the registry are indexed under Muscular Atrophy; 94 are open to participants now.
This study's enrollment of 25 is below the median of 33 across 335 interventional studies indexed under Muscular Atrophy.
Browse Muscular Atrophy studies →University Hospital, Bonn is the lead sponsor of 154 studies on the registry; 30 are open to participants now.
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Exclusion Criteria:
Control sham condition which performed the exercise with a fixed pressure of 20mmHg
Procedure: Sham-BFR
This intervention groups performed training on the operated limb with a BFR pressure corresponding to 60% of the individual limb occlusion pressure
Procedure: Blood Flow Restriction Training
The exercise protocol for the operated leg (with sham pressure of 20mmHg) consisted of four sets with 75 repetitions (reps) in total (1. Set: 30 reps, 2.-4. Set: 15 reps) with 30% of the individual one-repetition maximum for each exercise and were performed five times per week during the three-week outpatient rehabilitation.
The exercise protocol for the operated leg (with a BFR pressure of 60% of the LOP) consisted of four sets with 75 repetitions (reps) in total (1. Set: 30 reps, 2.-4. Set: 15 reps) with 30% of the individual one-repetition maximum for each exercise and were performed five times per week during the three-week outpatient rehabilitation.
Postoperative Pain
Postoperative Pain was assessed by visual analoge scale (0-100mm)
Time frame: Pre- to 6 weeks Post Rehabilitation
Muscle Strength
Isometric muscle strength was measured on a DDRobotec (Dynamic Devices AG, Zurich, Switzerland), a pneumatic, computer-controlled leg press
Time frame: Pre- to 6 weeks Post Rehabilitation
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
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University Hospital, Bonn