An interventional study of FMF Study Group and control group in FMF, sponsored by Ozge Gungor. Completed at 1 site in Turkey. Open to participants aged 6 Years to 15 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-04-18.
Sponsored by Ozge Gungor · Not applicable, Interventional, and Basic science
Among 66 studies in Bruxism with a site in Turkey — 11 open to participants now, 13 under way, none of them phase 3. Bruxism · Turkey.
Among the 66 studies in Bruxism with a site in Turkey, this one is the 3rd largest by enrollment of the 41 interventional ones, is one of 5 that started in 2021, is one of 39 with no phase, and was the 31st registered.
151 studies on the registry are indexed under Bruxism; 39 are open to participants now.
This study's enrollment of 90 is above the median of 39 across 94 interventional studies indexed under Bruxism.
Browse Bruxism studies →11 of the 66 studies in Bruxism with a site in Turkey are open now, in 1 country. Each count lists the studies.
Of the 15 Bruxism studies recruiting now, 8 (53%) set no upper age limit and 7 (47%) stop at 75 or younger; 2 take children under 18; 8 take healthy volunteers.
This study: 6 Years to 15 Years · all sexes · healthy volunteers too.
The full table on the hub →66 studies; the count open now beside each. This study's row is marked.
First in 2017; this study’s year is marked. 5 started in 2021.
Median enrollment 36 across the 41 interventional studies, 76 across the 25 observational. Of the 52 that completed or were terminated, 2 (4%) have results posted.
None of the 66 has an industry lead sponsor. The 10 most frequent:
Ozge Gungor is the lead sponsor of 4 studies on the registry; none are open to participants now.
Ozge Gungor has 1 study filed under Bruxism — fewer than ten, so there is no comparison to draw.
3 of the studies in Bruxism with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07640035Bilecik Seyh Edebali UniversitesiBotulinum Toxin-A for Bruxism Using Digital Occlusal Analysis | 2026-12-20 |
| NCT07241728Inonu UniversityBruxism and Diadinamic Current | 2026-12-20 |
| NCT07665398Necmettin Erbakan UniversityEffect of Marjoram, Vetiver, and Lavender Oil in the Treatment of Bruxism | 2026-12-31 |
Among the 66 studies in Bruxism with a site in Turkey, from their registry updates:
Aim: It is the clinical and radiological evaluation of oral hygiene, teeth and surrounding tissues in children and adolescents diagnosed with FMF and comparing the results with healthy individuals. Method: Our study included patients aged 6-15, 45 with FMF (study group) and 45 healthy (control group), who were referred from Akdeniz University Faculty of Medicine Pediatric Rheumatology Clinic and evaluated at Akdeniz University Faculty of Dentistry Pedodontics Clinic. MEFV gene mutations were investigated in the study group. After recording the demographic and clinical characteristics of both groups, intraoral examinations were performed and DMFT, dft, bruxism, tooth wear due to bruxism and gingival/plaque indexes were evaluated. Saliva pH, flow rate and buffering capacity were measured. Tooth age was determined by the Cameriere method, The mesio-distal dimensions of the teeth were measured on the plaster model.
In the study, DMFT, dft, bruxism, tooth wear due to bruxism, gingival index (MGI), plaque index (OHI-S), salivary pH, salivary flow rate, salivary buffering capacity, dental age, chronological age difference, mesio-distal dimensions of the teeth, and the presence of aphthous lesions were evaluated and compared between the study group consisting of children with FMF and the control group of healthy children.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
The study group was named 'Study group with FMF'.
Other: FMF Study Group
The control group consisting of healthy participants was called 'Healthy control group'.
Other: control group
In the study group consisting of children with FMF, DMFT, dft, bruxism, tooth wear due to bruxism, gingival index (MGI), plaque index (OHI-S), salivary pH, salivary flow rate, salivary buffering capacity, dental age, chronological age difference, mesio-distal dimensions of the teeth, and the presence of aphthous lesions were determined.
In the control group consisting of healthy children, DMFT, dft, bruxism, tooth wear due to bruxism, gingival index (MGI), plaque index (OHI-S), salivary pH, salivary flow rate, salivary buffering capacity, dental age, chronological age difference, mesio-distal dimensions of the teeth, and the presence of aphthous lesions were determined.
DMFT index
To determine the DMFT index score, decayed teeth in permanent teeth are indicated as "D", lost teeth extracted due to decay are indicated as "M", and filled teeth are indicated as "F". The DMFT index is calculated by adding the D, M, F values and dividing them by the total number of permanent teeth. An increase in the calculated scores indicates that oral and dental health is negatively affected.
Time frame: 3 months
dft index
The dft Index is the calculated form of the DMFT index for primary teeth. When calculating the dft group index, missing teeth are not included in the calculation. Because it is difficult to diagnose the reason for the loss of primary teeth and there is a high probability of error. For this reason, the number of decayed and filled teeth is calculated during the examination. Decayed teeth are indicated with "d" and filled teeth with "f". The dft index is calculated by adding the d and f values and dividing them by the total number of permanent teeth. An increase in the calculated scores indicates that oral and dental health is negatively affected
Time frame: 3 months
Saliva pH
Salivary pH was measured using pH indicator strips. A low pH (\<6.5) indicates an acidic environment and increases the risk of tooth demineralization and caries, whereas a high pH (\>7.5) indicates an alkaline state, which may be linked to decreased bacterial activity but may also indicate systemic conditions.
Time frame: 3 months
Unstimulated salivary flow rate
Unstimulated salivary flow rate is measured by collecting unstimulated saliva over a period of time and calculating the volume per minute. A low flow rate (\<0.1 mL/min) indicates hyposalivation, which increases the risk of caries and oral infection, while a high flow rate may be associated with conditions such as gastroesophageal reflux or medication effects.
Time frame: 3 months
Saliva buffering capacity
Saliva buffering capacity was measured using the GC Saliva Buffer Kit, which uses a scoring system based on color changes. A low buffering capacity indicates a higher risk of dental caries and enamel demineralization, whereas a high buffering capacity indicates better protection against acid attacks in the oral environment.
Time frame: 3 months
Simplified Oral Hygiene Index (OHI-S)
The Simplified Oral Hygiene Index (OHI-S) assesses oral cleanliness by measuring debris and calculus accumulation on selected tooth surfaces. Higher scores indicate poorer oral hygiene, while lower scores suggest better maintenance.
Time frame: 3 months
The Modified Gingival Index (MGI)
The Modified Gingival Index (MGI) evaluates gingival inflammation without probing, based on visual inspection. Higher scores reflect increased inflammation and potential periodontal issues.
Time frame: 3 months
Plan to share: No
No publications or documents are linked to this record.
Ran from Feb 2021 to primary completion in May 2021, 3 months.
Of 59 non-industry interventional studies with no phase under Bruxism, half reached primary completion within 8 months of starting (the median), counting those still running; a quarter within 3 and three quarters within 13. This study's 3 months is below that.
Counting every sponsor, half of 60 studies reached it within 7 months; a quarter within 3 and three quarters within 13.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
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Ozge Gungor