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Active, not recruitingNCT06884150Updated Mar 19, 2025

fNIRS-based Analysis and Evaluation of the Effect of Schroth Rehabilitation on Motor Functions in Adolescent Idiopathic Scoliosis (AIS)

An interventional study of Exercise in Scoliosis Idiopathic and Scoliosis; Adolescence, sponsored by Akdeniz University. Active, not recruiting at 1 site in Turkey. Open to participants aged 8 Years to 20 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-03-19.

Sponsored by Akdeniz University · Not applicable, Interventional, and Health services research

From the registry’s dates

  • Primary completion was expected by Sep 2025, 1 year 1 month ago, but the record still lists the study as active, not recruiting.
  • Registered 5 months after the study started (first participant enrolled Oct 2024, registered Mar 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
8 Years to 20 Years
Sex
All
01

Study summary

This study investigates the effects of Schroth-based rehabilitation on cortical dynamics, body awareness, and quality of life in individuals with Adolescent Idiopathic Scoliosis (AIS). Using fNIRS technology, motor control processes will be monitored, and the impact of rehabilitation on brain activity will be assessed.

A total of 30 participants (15 healthy and 15 with AIS), aged 8-16, will be examined, with pre- and post-rehabilitation comparisons. Measurements will include static posture, Y-Balance Test, Schroth walking, and brain activity recordings. SPM analysis will be used to assess brain signals, and quality of life and cosmetic deformity perception will be statistically evaluated.

The findings will contribute to the integration of neuroimaging into rehabilitation assessment, helping to develop more effective treatment strategies.

Read the detailed description

The evaluation of body schema and perception in the cortex of adolescent idiopathic scoliosis and the analysis of changes in brain regions functionally related to motor control and coordination between controls and the analysis of their developmental process with rehabilitation are very important in terms of contributing to the planning of a better effective rehabilitation process, increasing the patient's quality of life and evaluating the status of body representation related to the disease, its development and sustainability in daily life.

fNIRS-based postural control neuroimaging and analysis will provide pioneering information about body schema, postural balance, motor activation and their rehabilitation-oriented changes and brain plasticity, which will provide separate analysis of dynamic and static balance.

The changes created by body schema and perception in the cortex in individuals with AIS and the rehabilitation-oriented developmental process will be evaluated with functional near-infrared spectroscopy (fNIRS) solutions, specifically in motor control and coordination.

Another important deficiency in the literature is the evaluation of changes created by rehabilitation processes in the cortex. Thanks to neural plasticity, a system that tries to compensate for a dysfunction can be reorganized. Therefore, rehabilitation studies are also of great importance here. The observed significant lateralization and body schema changes may also be useful for creating personalized and targeted corrective postural exercises.

The portable fNIRS device is an effective neuroimaging and analysis method for monitoring motor control processes in cortical areas in subjects moving without any movement restrictions. Therefore, especially in terms of body representation, since performing measurements in a limited area where the patient's movement is not possible, such as fMRI, does not provide very accurate results, especially since the evaluation of the change process created by motor movements in the cortex does not yield very accurate results, cortical dynamics in AIS individuals will be evaluated with fNIRS.

02

Conditions studied

  • Scoliosis Idiopathic
  • Scoliosis; Adolescence

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Keywords

  • fNIRS
03

In context

Scoliosis

594 studies on the registry are indexed under Scoliosis; 139 are open to participants now.

This study's planned enrollment of 30 is below the median of 44 across 344 interventional studies indexed under Scoliosis.

Browse Scoliosis studies →

Lead sponsor

Akdeniz University is the lead sponsor of 289 studies on the registry; 60 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
8 Years to 20 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Being between the ages of 8-20
  • Being diagnosed with adolescent idiopathic scoliosis,
  • Accepting voluntary participation in the study.

Exclusion criteria

Exclusion Criteria:

  • History of tumor, vertebral malformation, trauma, epilepsy,
  • Having had spine or lower extremity surgery,
  • Having diagnosed psychiatric problems,
  • Having any disease that would prevent them from exercising,
  • Having rheumatic disease,
  • Having congenital deformity,
  • Being on another treatment for scoliosis during the study period,
  • Having received any conservative treatment for scoliosis or posture disorder in the last six months,
  • Having a body mass index over 25,
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Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
30 participants (estimated)

Study arms

  • No intervention
    Control group

    15 participant, healthy

  • Experimental
    Scoliosis group

    * Being between the ages of 8-16, * Being diagnosed with adolescent idiopathic scoliosis,

    Other: Exercise

Interventions

  • OtherExercise

    Participating in schroth exercises for 45 minutes, 2 days a week after receiving the relevant diagnosis

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What researchers measure

Primary outcomes

  1. fNIRs device

    After the installation and testing of the FNIRS device, recording and analysis are performed.

    Time frame: Between 3th month-9th month

  2. Y-balance test

    Determination of maximum percentage reach and combined score from the Y-balance test,

    Time frame: Between 3th month-9th month

Secondary outcomes

  1. Scoliosis Research Society-22 (SRS-22)

    Quality of life scale is determined with 5 sub-scores and a total score.

    Time frame: Between 3th month-9th month

07

Study locations

1 site
  • Akdeniz University
    Antalya, 07100, Turkey
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References and documents

Publications

  • Surgent OJ, Dadalko OI, Pickett KA, Travers BG. Balance and the brain: A review of structural brain correlates of postural balance and balance training in humans. Gait Posture. 2019 Jun;71:245-252. doi: 10.1016/j.gaitpost.2019.05.011. Epub 2019 May 6. PubMed 31082657 ↗

Related links

Individual participant data

Plan to share: Yes — A consent form will be obtained from the individuals participating in the study or their parents.

Supporting information: Icf

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 19, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06884150
Lead sponsor
Akdeniz University
Responsible party
Kadriye Tombak (PhD, Akdeniz University) — Principal investigator
First posted
Mar 19, 2025
Start date
Oct 1, 2024
Primary completion
Sep 2, 2025 (estimated)
Completion
Jan 2, 2026 (estimated)
Last update
Mar 19, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.

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