An interventional study of standard medical care and structured pulmonary rehabilitation in Chronic Lung Disease, Quality of Life and Respiratory Function Impaired, sponsored by Horus University. Completed at 1 site in Egypt. Open to participants aged 6 Years to 16 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-03-11.
Sponsored by Horus University · Not applicable, Interventional, and Other
Chronic lung diseases (CLDs) such as asthma, cystic fibrosis, and bronchopulmonary dysplasia significantly impact pediatric patients' respiratory function and overall well-being. Pulmonary rehabilitation (PR) has been shown to improve lung function, exercise tolerance, and quality of life in affected individuals. However, limited research has been conducted on PR implementation in Egypt.
Pulmonary rehabilitation significantly enhances respiratory function, exercise capacity, and quality of life in pediatric patients with CLDs while reducing healthcare utilization. These findings highlight the necessity of integrating structured PR programs into pediatric respiratory care in Egypt.
3,303 studies on the registry are indexed under Lung Diseases; 355 are open to participants now.
This study's enrollment of 400 is above the median of 72 across 2,118 interventional studies indexed under Lung Diseases.
Browse Lung Diseases studies →Horus University is the lead sponsor of 31 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients receiving standard medical care without structured pulmonary rehabilitation.
Other: standard medical care
The experimental group underwent a 12-week structured pulmonary rehabilitation program.
Other: structured pulmonary rehabilitation
standard medical care
structured pulmonary rehabilitation program including: * Physical Therapy: Breathing exercises, airway clearance techniques, inspiratory muscle training. * Pediatrics \& Chest Medicine: Medical supervision, optimization of pharmacological treatment. * Physiology: Monitoring pulmonary function and physiological responses to exercise. * Public Health: Evaluating program feasibility and its impact on healthcare utilization.
Forced Expiratory Volume in One Second
FEV₁ is the volume of air that a person can forcefully exhale in the first second of a forced breath after taking a deep inhalation. Interpretation of FEV₁: ≥80% of predicted → Normal 60-79% of predicted → Mild obstruction 40-59% of predicted → Moderate obstruction \<40% of predicted → Severe obstruction
Time frame: at basline and after 12-weeks of intervention
Forced Vital Capacity
FVC is the total volume of air that can be forcefully exhaled after taking the deepest possible breath. Normal Values: Typically ≥80% of the predicted value. Obstructive Lung Disease: FVC may be normal or slightly reduced. Restrictive Lung Disease: FVC is significantly reduced due to decreased lung compliance or lung volume.
Time frame: at basline and after 12-weeks of intervention
Peak Expiratory Flow Rate
PEFR is the maximum speed of expiration achieved after full lung inflation. It is measured in liters per minute (L/min). ormal values depend on age, sex, and height: Adult males: 450-700 L/min Adult females: 300-500 L/min Reduced PEFR: Suggests airway obstruction, such as in asthma or COPD.
Time frame: at basline and after 12-weeks of intervention
Hospitalization Frequency
Hospitalization frequency refers to the number of times a patient is admitted to a hospital due to disease exacerbation, complications, or treatment failure. Number of hospital admissions within a specific time frame (e.g., per year). Length of hospital stay (days per admission). Emergency department visits requiring inpatient care.
Time frame: at basline and after 12-weeks of intervention
Medication Dependency
Medication dependency refers to the extent to which a patient relies on pharmacological treatment to manage symptoms and maintain functional health. Frequency and dosage of medication use. Number of rescue medication uses (e.g., bronchodilators in asthma). Reduction or discontinuation of medication over time.
Time frame: at basline and after 12-weeks of intervention
Parental Satisfaction with Treatment
Parental satisfaction refers to how parents perceive the effectiveness, convenience, and overall impact of their child's treatment plan. Standardized satisfaction surveys (e.g., Likert scale questionnaires). Interviews or focus groups with parents. Feedback on treatment effectiveness, side effects, accessibility, and ease of use.
Time frame: at basline and after 12-weeks of intervention
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Horus University