An interventional study of Whole-Body Electromyostimulation and Resistance exercise in Osteopenia and Cardiometabolic Conditions, sponsored by University of Erlangen-Nürnberg Medical School. Completed at 2 sites in Germany. Open to female participants aged 18 Years to 30 Years. Per ClinicalTrials.gov, last updated 2026-01-30.
Sponsored by University of Erlangen-Nürnberg Medical School · Not applicable, Interventional, and Other
Due to their high workload and unfavorable working position, young female dentists are particularly at risk of cardiometabolic diseases and an early reduction in bone mineral density (BMD). With focus on the latter issue, short bouts of resistance exercise with high strain magnitude and velocity are commonly considered to be a feasible option to prevent bone loss in the early years of young adulthood. In parallel, whole-body electromyostimulation (WB-EMS) a trainings technology able address all main muscle groups simultaneously, however with dedicated exercise intensity might be a time-effective, joint friendly and safe option to maintain BMD in people unable or unmotivated to exercise conventionally. In the present study, we aim to compare the effects of a single session of WB-EMS versus high intensity, high velocity resistance exercise on biomarkers of bone formation (Procollagen type 1 N propeptide, P1NP) and resorption (C-terminal telopeptide of type I collagen, CTX-I). We hypothesize that no clinically relevant different effects on P1NP and CTX-I were determined.
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This study's enrollment of 16 is below the median of 60 across 359 interventional studies indexed under Bone Diseases, Metabolic.
Browse Bone Diseases, Metabolic studies →University of Erlangen-Nürnberg Medical School is the lead sponsor of 267 studies on the registry; 51 are open to participants now.
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Exclusion Criteria:
One single bout of whole-body electromyostimulation (20 min, bipolar, 85 Hz, 350 µs, rectangular, 6s of impulse, 4s of rest)
Other: Whole-Body Electromyostimulation
High intensity, high velocity resistance exercise (30 min, 5-6 exercises, 3 sets at 60-85% 1RM)
Other: Resistance exercise
20 min of WB-EMS (bipolar, 85 Hz, 350 µs, 6s impulse - 4s impulse break)
High-intensity/high velocity multiple set resistance exercise
Changes for C-terminal telopeptide of type I collagen from pre- to 15 min post-exercise
Changes for C-terminal telopeptide of type I collagen (CTX-I) serum levels from pre- to 15 min post-exercise as determined by blood samples
Time frame: Immediately pre-exercise to 15 min post exercise of a single exercise session
Changes for Procollagen type 1 N propeptide from pre- to 15 min post-exercise
Changes for Procollagen type 1 N propeptide (P1NP) serum levels from pre- to 15 min post-exercise as determined by blood samples
Time frame: Immediately pre-exercise to 15 min post exercise of a single exercise session
Changes for resting glucose from pre- to 15 min post-exercise
Changes for resting glucose serum levels from pre- to 15 min post-exercise as determined by blood samples
Time frame: Immediately pr to 15 min post-exercise of a single exercise session
Changes for hemoglobin A1c from pre- to 15 min post-exercise
Changes for hemoglobin A1c (HBA1C) serum levels from pre- to 15 min post-exercise as determined by blood samples
Time frame: Immediately pre- to 15 min post-exercise of a single exercise session
Plan to share: Undecided
This study is completed, as verified in Jun 2025. You cannot join it, but the record below documents what was studied.
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University of Erlangen-Nürnberg Medical School