ClinicalTrials.gg
RecruitingNCT06810817Updated Sep 17, 2026

Transcranial Direct Current Stimulation and Cognitive Behavioural Programme on Post-stroke Fatigue

An interventional study of tDCS & cognitive behavioral programme with home-based physical training and sham tDCS & cognitive behavioral programme with home-based physical training in Stroke, sponsored by The Hong Kong Polytechnic University. Recruiting at 1 site in Hong Kong. Open to participants aged 50 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-09-17.

Sponsored by The Hong Kong Polytechnic University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 3 months after the study started (first participant enrolled Oct 2024, registered Jan 2025).
  • Started Oct 2024; still recruiting 2 years later.
Phase
Not applicable
Study type
Interventional
Enrollment
75
Allocation
Randomized
Ages
50 Years to 80 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 73 studies in Stroke by The Hong Kong Polytechnic University — 32 open to participants now, 34 under way, none of them phase 3. Stroke · The Hong Kong Polytechnic University.

Planned enrollment
25th of 70
75 · median 60
Started
2024
with 9 others
No phase
70 of 73
30 open now
Primary completion
2026-12
later than 7 of 33 live
Registered
55th of 73
by date

Among the 73 studies in Stroke by The Hong Kong Polytechnic University, this one is the 25th largest by planned enrollment of the 70 interventional ones that give a count, is one of 10 that started in 2024, is one of 70 with no phase, reaches primary completion later than 7 of the 33 other live ones, and was the 55th registered.

Stroke

8,255 studies on the registry are indexed under Stroke; 2,056 are open to participants now.

Browse Stroke studies →

Open to participants now

32 of the 73 studies in Stroke by The Hong Kong Polytechnic University are open now, in 3 countries. Recruiting first, the newest first:

26 more — sign in →

By country, each count listing its studies:

All 32 open studies →

Where they have run

Who these studies take

Of the 1,415 Stroke studies recruiting now, 697 (49%) set no upper age limit and 280 (20%) stop at 75 or younger; 77 take children under 18; 196 take healthy volunteers.

This study: 50 Years to 80 Years · all sexes · no healthy volunteers.

The full table on the hub →

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 73 studies in Stroke by The Hong Kong Polytechnic University, or all of them as a file.
02

Study summary

This study aims to evaluate the effect of transcranial direct current stimulation and cognitive behavioural programme on fatigue and its related outcomes among people with stroke.

Read the detailed description

This study will adopt a randomized controlled trial. Participants will be randomized into one of the 3 groups. One group will receive transcranial direct current stimulation and cognitive behavioural programme with home-based physical training. Another group will receive sham transcranial direct current stimulation and cognitive behavioural programme with home-based physical training. One group will receive home-based physical training only.

03

Conditions studied

  • Stroke

Browse trials for

04

Who can participate

Ages eligible
50 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • diagnosed with stroke at least 6 months ago
  • Fatigue Assessment Scale score ≥20
  • cognitively intact

Exclusion criteria

Exclusion Criteria:

  • Unstable medical conditions leading to fatigue
  • Under any clinical trials
  • with any other neurological diseases
  • history of
  • to tDCS
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

TIA (transient ischaemic attack)

A “mini-stroke”: temporary stroke-like symptoms caused by reduced blood flow to part of the brain, spinal cord or eye, without signs of a new stroke on a scan.

Stroke symptoms need emergency care at once, even if they go away.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
75 participants (estimated)

Study arms

  • Experimental
    tDCS and cognitive behavioural programme with physical training

    Combination Product: tDCS & cognitive behavioral programme with home-based physical training

  • Active comparator
    sham tDCS and cognitive behavioural programme with physical training

    Behavioral: sham tDCS & cognitive behavioral programme with home-based physical training

  • Active comparator
    physical training

    Behavioral: physical training

Interventions

  • Combination producttDCS & cognitive behavioral programme with home-based physical training

    Participants will receive 16 sessions of tDCS and 7 sessions of cognitive behavioral programme over 8 weeks and have physical training at home for 8 weeks.

  • Behavioralsham tDCS & cognitive behavioral programme with home-based physical training

    Participants will receive 16 sessions of sham-tDCS and 7 sessions of cognitive behavioral programme over 8 weeks and have physical training at home for 8 weeks.

  • Behavioralphysical training

    Participants will have physical training at home for 8 weeks.

06

What researchers measure

Primary outcomes

  1. Fatigue Assessment Scale

    Time frame: baseline, in the middle during the intervention, immediate post-intervention, 1- and 3-month after the completion of the intervention

Secondary outcomes

  1. Pittsburgh Sleep Quality Index

    Time frame: baseline, in the middle during the intervention, immediate post-intervention, 1- and 3-month after the completion of the intervention

  2. Geriatric Depression Scale

    Time frame: baseline, in the middle during the intervention, immediate post-intervention, 1- and 3-month after the completion of the intervention

  3. Reintegration to Normal Living Index

    Time frame: baseline, in the middle during the intervention, immediate post-intervention, 1- and 3-month after the completion of the intervention

  4. Cardio-ankle vascular index

    Time frame: baseline, in the middle during the intervention, immediate post-intervention, 1- and 3-month after the completion of the intervention

  5. performance fatigue index

    Time frame: baseline, in the middle during the intervention, immediate post-intervention, 1- and 3-month after the completion of the intervention

  6. psychomotor vigilance task

    Time frame: baseline, in the middle during the intervention, immediate post-intervention, 1- and 3-month after the completion of the intervention

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Oct 2024 (actual). Primary completion is estimated for Dec 2026, 26 months after the start.

Of 3,108 non-industry interventional studies with no phase under Stroke, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 46. This study's planned 26 months is above that.

Counting every sponsor, half of 3,252 studies reached it within 23 months; a quarter within 10 and three quarters within 46.

How these figures are worked out, and which studies are left out of them.

Registered
Jan 28, 2025
First posted
Feb 6, 2025
StartActual
Oct 28, 2024
Primary completionEst.
Dec 2026
CompletionEst.
Dec 2026
Last update
Sep 17, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 17, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06810817
Responsible party
Shamay Ng (Prof, The Hong Kong Polytechnic University) — Principal investigator
First posted
Feb 6, 2025
Start date
Oct 28, 2024
Primary completion
Dec 2026 (estimated)
Completion
Dec 2026 (estimated)
Last update
Sep 17, 2026

Study contacts

Shamay NG
Contact
shamay.ng@polyu.edu.hk
852-2766-4889

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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