An interventional study of active tDCS with dual-task training and sham tDCS with dual-task training in Stroke and Cortical Excitability, sponsored by The Hong Kong Polytechnic University. Recruiting at 1 site in Hong Kong. Open to participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2026-10-14.
Sponsored by The Hong Kong Polytechnic University · Not applicable, Interventional, and Treatment
Among 73 studies in Stroke by The Hong Kong Polytechnic University — 32 open to participants now, 34 under way, none of them phase 3. Stroke · The Hong Kong Polytechnic University.
Among the 73 studies in Stroke by The Hong Kong Polytechnic University, this one is the 26th largest by planned enrollment of the 70 interventional ones that give a count, is one of 8 that started in 2025, is one of 70 with no phase, reaches primary completion later than 16 of the 33 other live ones, and was the 53rd registered.
8,255 studies on the registry are indexed under Stroke; 2,056 are open to participants now.
Browse Stroke studies →32 of the 73 studies in Stroke by The Hong Kong Polytechnic University are open now, in 3 countries. Recruiting first, the newest first:
The Hong Kong Polytechnic University · Sites in Hong Kong
Ages 18–80 · Healthy volunteers
The Hong Kong Polytechnic University · Sites in Hong Kong
Ages 18+
The Hong Kong Polytechnic University · Sites in Hong Kong
Ages 18–80
The Hong Kong Polytechnic University · Sites in Hong Kong, Singapore
Ages 21–79 · Healthy volunteers
The Hong Kong Polytechnic University · Sites in Hong Kong
Ages 50+
By country, each count listing its studies:
Of the 1,415 Stroke studies recruiting now, 697 (49%) set no upper age limit and 280 (20%) stop at 75 or younger; 77 take children under 18; 196 take healthy volunteers.
This study: 50 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
73 studies; the count open now beside each. This study's row is marked.
First in 2008; this study’s year is marked. 8 started in 2025.
This study's planned enrollment of 72 is above the median of 49 across 6,024 interventional studies indexed under Stroke.
Median enrollment 60 across the 70 interventional studies, 303 across the 2 observational. Of the 33 that completed or were terminated, 2 (6%) have results posted.
This tab as a report to print or save as PDF → With an account.
The Hong Kong Polytechnic University is the lead sponsor of 681 studies on the registry; 259 are open to participants now.
13 of the studies in Stroke by The Hong Kong Polytechnic University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06810817The Hong Kong Polytechnic UniversityTranscranial Direct Current Stimulation and Cognitive Behavioural Programme on Post-stroke Fatigue | 2026-12 |
| NCT07719517The Hong Kong Polytechnic UniversityMorning Activation to Improve Mood After Stroke | 2026-12 |
| NCT05615610The Hong Kong Polytechnic UniversityEffects of Transcutaneous Electrical Nerve Stimulation on Cognitive Function and Upper Limb Motor Function in People With Chronic Stroke | 2026-12-15 |
| NCT03631628The Hong Kong Polytechnic UniversityUpper Limb Mirror Therapy With Bilateral Transcutaneous Electrical Nerve Stimulation to Improve Upper Limb Functions in Patients With Stroke | 2026-12-31 |
| NCT06509789The Hong Kong Polytechnic UniversityPriming Theta Burst Stimulation for Stroke: A Study of Intensity | 2026-12-31 |
Add all 13 to your calendar (.ics) → With an account.
Among the 73 studies in Stroke by The Hong Kong Polytechnic University, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This study aims to evaluate the effects of tDCS combined with cognitive-motor training on dual-task interference during walking and foot pedaling, alongside corresponding alterations in brain activity assessed via fNIRS. Additionally, an fMRI component was conducted as a nested sub-study for deep mechanistic exploration.
In China, the prevalence of stroke increased by 106.0% (93.7-118.8) between 1990 and 2019, highlighting the persistent and substantial burden of this condition. Post-stroke recovery, particularly the ability to achieve community ambulation, plays a critical role in improving health-related quality of life. Effective community ambulation in daily life requires the ability to dual-task-namely, to perform concurrent tasks requiring attentional resources while maintaining walking function and balance. Emerging evidence suggests that stroke survivors face greater challenges in walking function and dual-task balance compared to their age-matched, able-bodied counterparts. For instance, when tasked with recalling a shopping list while walking, stroke patients exhibit a more pronounced decline in both walking speed and cognitive performance relative to control groups. Given the necessity for stroke survivors to reintegrate into the community, it is imperative to thoroughly investigate this phenomenon of cognitive-motor interference.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
patients receive three active tDCS and three dual motor-cognitive exercise training per week for four weeks.
Other: active tDCS with dual-task training
Patients receive three sham tDCS and three dual cognitive-motor exercise training per week for four weeks.
Other: sham tDCS with dual-task training
participants receive three 20-minute active tDCS treatment and three 60-minute COGMOTION dual-task exercise sessions per week for four consecutive weeks.
participants receive three 20-minute sham tDCS treatment and three 60-minute COGMOTION dual-task exercise sessions per week for four consecutive weeks.
Dual-task self-paced walking--gait speed
Gait speed under dual-task walking condition will be recorded
Time frame: Through study completion, an average of 1 year
Dual-task self-paced walking--cognitive performance
Number of correct responses will be measured during dual-task conditions
Time frame: Through study completion, an average of 1 year
Dual-task self-paced walking--gait performance 1
Gait cadence will be measured during dual-task walking
Time frame: Through study completion, an average of 1 year
Dual-task self-paced walking--gait performance 2
Stride length will be measured during dual-task walking
Time frame: Through study completion, an average of 1 year
Dual-task self-paced walking--gait performance 3
Dor-Plantar Range under dual-task walking will be recorded
Time frame: Through study completion, an average of 1 year
Dual-task self-paced walking--cognitive performance 1
Correct reaction time under dual-task walking will be recorded
Time frame: Through study completion, an average of 1 year
Oxyhemoglobin concentration changes of the brain
Oxyhemoglobin concentration changes will be measured using functional near infra-red spectroscopy during dual-task walking
Time frame: Through study completion, an average of 1 year
Dual-task pedaling--cadence
cadence under dual-task foot pedaling will be recorded
Time frame: Through study completion, an average of 1 year
Dual-task pedaling--cognitive performance 1
Number of correct responses under dual-task foot pedaling will be recorded
Time frame: Through study completion, an average of 1 year
Blood oxygenation level changes of the brain
Blood oxygenation level changes will be measured using Magnetic Resonance Imaging during dual-task foot pedaling
Time frame: Through study completion, an average of 1 year
tDCS adverse event
number of patients who report an adverse event will be recorded.
Time frame: Through study completion, an average of 1 year
Dual-task pedaling--peak angular velocity
Peak angular (dorsi-plantar flexion) velocity under dual-task foot pedaling will be recorded
Time frame: Through study completion, an average of 1 year
Dual-task pedaling--Dorsi and Plantar range
Dorsi and Plantar range during dual-task foot pedaling will be recorded
Time frame: Through study completion, an average of 1 year
Dual-task walking--truning mobility
number of steps in turn will be recorded during dual-task walking
Time frame: Through study completion, an average of 1 year
Single-task walking speed
10-meter walking test will be used to assess single-task walking speed in meters per second
Time frame: Through study completion, an average of 1 year
Balance 1
Mini Balance Evaluation Systems Test will be used to assess postural control, with total points from 0-28. Higher points indicate better performance.
Time frame: Through study completion, an average of 1 year
Balance 2
Activities-specific Balance Confidence Scale will be used to assess confidence of functional balance performance, with total points from 0-100. Higher points indicate better performance.
Time frame: Through study completion, an average of 1 year
Cognitive performance
Stroop color word test will be used to assess executive function
Time frame: Through study completion, an average of 1 year
Cognitive performance 1
Montreal Cognitive Assessment will be used to assess global cognition, with total points from 0-30. Higher points indicate better performance.
Time frame: before the initiation of training
Cognitive performance 2
Trail Making Test will be used to assess executive function
Time frame: Through study completion, an average of 1 year
Fall incidence
Monthly telephone interviews for recording fall incidence
Time frame: Through study completion, an average of a year
dual-task maximal walking--gait performance
Walking time under dual-task walking at maximal speed will be recorded
Time frame: Through study completion, an average of 1 year
dual-task maximal walking--cognitive performance
Accuracy under dual-task walking at maximal speed will be recorded
Time frame: Through study completion, an average of 1 year
Plan to share: Yes
Supporting information: Study protocol, Statistical analysis plan, Informed consent form, Clinical study report
No publications or documents are linked to this record.
Started Jan 2025 (actual). Primary completion is estimated for Apr 2027, 27 months after the start.
Of 3,108 non-industry interventional studies with no phase under Stroke, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 46. This study's planned 27 months is above that.
Counting every sponsor, half of 3,252 studies reached it within 23 months; a quarter within 10 and three quarters within 46.
Since we started tracking on Sep 25, 2026, the dates moved once, on Oct 14, 2026: primary completion Dec 2026 → Apr 2027 and completion Dec 2026 → Apr 2027.
Earlier changes are on the record history on ClinicalTrials.gov ↗
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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The Hong Kong Polytechnic University →