An observational study in Chronic Kidney Disease Stage 5 and Heart Failure, sponsored by Moscow Regional Research and Clinical Institute (MONIKI). Completed at 1 site in Russian Federation. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2025-02-04.
Sponsored by Moscow Regional Research and Clinical Institute (MONIKI) · Observational
Heart failure with preserved / high cardiac output is a well-known syndrome in patients with high-flow arteriovenous fistula (AVF). However, the threshold for classifying an AVF as high-flow is currently undefined. Cardio-fistular recirculation (CFR) is often used as a criterion, with values greater than 25-30% considered cardiotoxic and associated with adverse outcomes. Additionally, CFR is one of the few easily modifiable risk factors through surgical reduction of AVF volume blood flow (Qa).
The study aimed to evaluate the extent of involution of heart structural and functional changes following Qa reduction in patients with heart failure and CFR > 25%.
3,840 studies on the registry are indexed under Kidney Diseases; 500 are open to participants now.
This study's enrollment of 86 is below the median of 192 across 1,033 observational studies indexed under Kidney Diseases.
Browse Kidney Diseases studies →Moscow Regional Research and Clinical Institute (MONIKI) is the lead sponsor of 14 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Adult patients receiving maintenance hemodialysis treatment
Exclusion Criteria:
Patients with NYHA I-II heart failure
Patients with NYHA III-IV heart failure
Left ventricular ejection fraction
Time frame: Before and at 6 months after surgery
Estimated pulmonary artery pressure
Time frame: Before and at 6 months after surgery
E/A ratio
Time frame: Before and at 6 months after surgery
NT-proBNP serum concentration
Time frame: Before and at 6 months after surgery
Plan to share: Yes — Upon reasonable request.
Supporting information: Study protocol, Sap, Icf, Csr, Analytic code
No publications or documents are linked to this record.
This study is completed, as verified in Jan 2025. You cannot join it, but the record below documents what was studied.
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Moscow Regional Research and Clinical Institute (MONIKI)