An observational study in Chronic Rhinosinusitis (CRS) with and Without Nasal Polyps, sponsored by Nanjing First Hospital, Nanjing Medical University. Active, not recruiting at 1 site in China. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-12-17.
Sponsored by Nanjing First Hospital, Nanjing Medical University · Observational
The purpose of this observational study was to examine whether preoperative indicators correlate with intraoperative bleeding to facilitate control of intraoperative bleeding.
In this study, we analysed the effect of preoperative inflammation on intraoperative haemorrhage at the subjective and objective levels by measuring a number of indicators (including Vit D, Ca, P, and some ratios) in the blood specimens and by three scales.Blood test indicators can be obtained from routine tests.Three scales were obtained by the researcher after interviewing the patients, Symptom Score (0-15), where higher scores indicate more severe symptoms, Lund-Kennedy Score (0-6), where higher scores indicate higher levels of localised inflammation, Lund-Mackay Score (0-12 unilaterally and 24 bilaterally), where higher scores indicate higher levels of inflammation, and Lund-Mackay Score (0-12 unilaterally and 24 bilaterally), where higher scores indicate higher levels of inflammation.Lund-Mackay score (0-12 unilaterally, 24 bilaterally), where higher scores represent higher levels of inflammation.Final correlation of blood test indices and three scale scores with intraoperative.
223 studies on the registry are indexed under Blood Loss, Surgical; 39 are open to participants now.
This study's planned enrollment of 100 is below the median of 154 across 50 observational studies indexed under Blood Loss, Surgical.
Browse Blood Loss, Surgical studies →Nanjing First Hospital, Nanjing Medical University is the lead sponsor of 220 studies on the registry; 107 are open to participants now.
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Diagnosed with chronic sinusitis
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Clinical diagnosis of chronic rhinosinusitis
Exclusion Criteria:
Sinus cyst Upper respiratory tract infection in the last 1 week Use of antiepileptic drugs Use of aspirin Use of anticoagulant or antiplatelet drugs
chronic rhinosinusitis with/without nasal polys.
Other: without interventios.
without interventios.
Intraoperative haemorrhage
Intraoperative haemorrhage was grouped with a cut-off value of 150 ml and divided into \<150 ml (normal haemorrhage group) and ≥150 ml (high haemorrhage group).
Time frame: 2024/11/1-2025/7/31
Symptom system
Symptom system (0-15 scores), assessed in five areas: nasal congestion, runny nose, reduced sense of smell, head and face swelling, and sleep disturbances, where higher scores represent more severe symptoms.
Time frame: 2024/11/1-2025/7/31
Lund-Kennedy system
Lund-Kennedy system (0-6 scores), assessed under nasal endoscopy in terms of polyps, oedema and nasal secretions, where a higher score represents a higher level of local inflammation.
Time frame: 2024/11/1-2025/7/31
Lund-Mackay system
The Lund-Mackay system (0-12 unilaterally, 24 points in total bilaterally) analyses the inflammatory status within each sinus and the assessment of whether the sinonasal complex is obstructed in two major ways, where higher scores represent higher levels of inflammation.
Time frame: 2024/11/1-2025/7/31
Plan to share: No
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This study is active, not recruiting, as verified in Nov 2024. You cannot join it, but the record below documents what was studied.
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Nanjing First Hospital, Nanjing Medical University →