ClinicalTrials.gg
RecruitingNCT06726187Updated Jul 17, 2026

DSM-5 Personality Disorders in Adults With Autism

An observational study in Autism Spectrum Disorder, sponsored by Parnassia Groep. Recruiting at 1 site in Netherlands. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-07-17.

Primary conditionAutistic DisorderRegistry: Autism Spectrum DisorderReclassifiedWhy we changed it
Registry
Autism Spectrum Disorder — the first condition term the registry derived for this study.
ClinicalTrials.gg
Autistic Disorder
Why
  1. The study's listed conditions name Autistic Disorder, a narrower term within Autism Spectrum Disorder.
Confidence
High: the new condition is named in the study's own listed conditions. Of 351 hand-checked studies reclassified this way, 68% were exactly right and 84% in the right disease family; the registry's first term was right for 5% (measured 2026-10-21). How we classify →
Wrong?
Tell us the study's main condition →

Sponsored by Parnassia Groep · Observational

From the registry’s dates

  • Started Mar 2024; still recruiting 2 years 8 months later.
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
102
Ages
18 Years and older
Sex
All
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Study summary

Rationale: Self-report measures are frequently used for research and clinical assessments of adults with autism spectrum disorder (ASD). However, there has been little research examining agreement between self-report and informant-report in this population. Reliable self-report measures are essential for conducting research with and providing high quality clinical services for adults with autism spectrum disorder.

Objective: This study aims to examine the usefulness of self-report of DSM-5-TR PD traits in adults with ASD compared to informant-reports by administering the self-report screening measure of the Structured Clinical Interview for DSM-5 Screening Personality Questionnaire (SCID-5-SPQ).

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Conditions studied

  • Autism Spectrum Disorder

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Keywords

  • Autism
  • Personality disorder
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In context

Autistic Disorder Reclassified

1,030 studies on the registry are indexed under Autistic Disorder; 266 are open to participants now.

This study's planned enrollment of 102 is close to the median of 101 across 189 observational studies indexed under Autistic Disorder.

Browse Autistic Disorder studies →

Lead sponsor

Parnassia Groep is the lead sponsor of 5 studies on the registry; 2 are open to participants now.

Compared within Autistic Disorder, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Autism Spectrum Disorder. The counts are of registry records indexed under each term, refreshed daily. How we classify →

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Adult males and females (age ≥ 18 years), clinically diagnosed with ASD by a psychologist or a psychiatrist, without intellectual disability, and their informants. ASD participants will be recruited from Sarr Autism Rotterdam, the Netherlands, specialized in psychodiagnostic assessment and treatment for children, adolescents, and adults with ASD. Sarr is part of Parnassia Groep, multisite mental health institute in the Netherlands.

Eligibility criteria

Inclusion criteria Inclusion criteria for ASD participants: (1) primary diagnosis of ASD according to the , (2) age 18+ years, (3) no intellectual disability, and (4) at least having completed a primary and secondary education.

Inclusion criteria for informants:

Participants were asked to identify individuals who knew them well and were capable of providing accurate descriptions of their personality traits, preferably informants that cohabited with the participants. When cohabitants were unavailable, participants were asked to identify "the person who knows you best." Additionally, eligibility of informants for inclusion required that, historically, the informant and the participant talked at least monthly and interacted face-to-face at least yearly.

Exclusion criteria Exclusion criteria for ASD participants: (1) no ASD diagnosis, (2) current substance abuse, (3) psychotic disorders, (4) schizophrenia, (5) eating disorder, (6), mental retardation (IQ\<80), (7) suicidal ideations and (8) age \<18 years.

Exclusion criteria for informants: (1) age \<18 years, (2) intellectual disability, and (3) not being able to state and/or recognize psychological and problematic functioning of their participating relative with ASD.

Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

DSM diagnostic criteria

The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.

05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
102 participants (estimated)
Target follow-up
1 Day
Patient registry
Yes

Groups and cohorts

  • 1

    Adults with autism spectrum disorder

    Other: Structured Clinical Interview for DSM-5 Screening Personality Questionnaire (SCID-5-SPQ).

  • 2

    The relative of the adult with autism spectrum disorder

    Other: Structured Clinical Interview for DSM-5 Screening Personality Questionnaire (SCID-5-SPQ).

Interventions

  • OtherStructured Clinical Interview for DSM-5 Screening Personality Questionnaire (SCID-5-SPQ).

    Screening questionnaire

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What researchers measure

Primary outcomes

  1. Score SCID-5-PD

    The main study parameters are the item scores on the Structured Clinical Interview for DSM-5 Personality Disorders (SCID-5-PD). The participant can score with Yes and No on the questions. The scoring parameters are 0 (No) and 1 (Yes). This is for all items. A higher score means that the participant scores on that personality item.

    Time frame: 1 day

07

Study locations

1 of 1 sites recruiting
  • Sarr - Parnassia Groep Antes
    Rotterdam, Netherlands
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 17, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06726187
Lead sponsor
Parnassia Groep
Responsible party
Sponsor
First posted
Dec 10, 2024
Start date
Mar 1, 2024
Primary completion
Jan 28, 2027 (estimated)
Completion
Jan 29, 2027 (estimated)
Last update
Jul 17, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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