An interventional study of Family Resilience And Mind-body Enhancement" (FRAME) in Autism, sponsored by The University of Hong Kong. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-11-05.
Sponsored by The University of Hong Kong · Not applicable, Interventional, and Supportive care
The goal of this clinical trial is to learn if a family resilience and mind-body programme called "Family Resilience And Mind-body Enhancement" (FRAME) works to support families with autistic children. The main question it aims to answer is:
- What are the effectiveness and acceptability of FRAME for families with autistic children?
Researchers will compare FRAME to a waitlist group (participants who receive the programme after the study ends) to see if FRAME makes a difference.
Participants will:
1,030 studies on the registry are indexed under Autistic Disorder; 266 are open to participants now.
This study's planned enrollment of 114 is above the median of 49 across 811 interventional studies indexed under Autistic Disorder.
Browse Autistic Disorder studies →The University of Hong Kong is the lead sponsor of 1,292 studies on the registry; 348 are open to participants now.
Of its 9 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Participants are eligible if they:
Exclusion Criteria:
Individuals will be excluded if they
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Behavioral: Family Resilience And Mind-body Enhancement" (FRAME)
Control group will undergo intervention after completing all assessments
Family Resilience And Mind-body Enhancement (FRAME) is a parent-focused mind-body intervention designed for parents of autistic children. Across six weekly 2hr sessions, FRAME integrates mind-body practices - which have demonstrated efficacy among families with autistic children - with Walsh's three domains of family resilience, namely belief systems, organizational patterns and communication processes. The mind-body component will be adapted from MYmind - an established mindfulness-based intervention specifically developed for children with ASD/ADHD and their parents. Each session follows a standard format: a review on home practice, guided mind-body practices and structured group discussions and activities targeting each domain of family resilience. Session content progresses sequentially across the six sessions. Between sessions, participants are encouraged to practise daily using the workbook provided.
Parenting stress
Parenting Stress Index - Short Form (PSI-SF)
Time frame: From baseline (T0) to the end of treatment at 6 weeks (T1)
Parenting stress
Parenting Stress Index - Short Form (PSI-SF)
Time frame: From baseline (T0) to the end of treatment at 18 weeks (T2)
Parental distress
21-item Depression Anxiety Stress Scale-21 (DASS-21)
Time frame: Baseline (T0), 6 weeks (T1), 18 weeks (T2)
Parental Well-being
5-item World Health Organization Well-Being Index (WHO-5)
Time frame: Baseline (T0), 6 weeks (T1), 18 weeks (T2)
Mindful parenting
31-item Interpersonal Mindfulness in Parenting Scale (IM-P)
Time frame: Baseline (T0), 6 weeks (T1), 18 weeks (T2)
Child emotional and behavioural and problems
Parent and teacher-report Strengths and Difficulties Questionnaire (SDQ)
Time frame: Baseline (T0), 6 weeks (T1), 18 weeks (T2)
Sibling emotional and behavioural problems (only for families with more than one child)
Parent-report Strengths and Difficulties Questionnaire (SDQ)
Time frame: Baseline (T0), 6 weeks (T1), 18 weeks (T2)
Parent-sibling relationship (only for families with more than one child)
Parent-report parent-child dysfunctional interaction subscale of PSI-SF
Time frame: Baseline (T0), 6 weeks (T1), 18 weeks (T2)
Parent-child relationship
Parent-child dysfunctional interaction subscale of PSI-SF
Time frame: Baseline (T0), 6 weeks (T1), 18 weeks (T2)
Marital satisfaction
3-item Kansas Marital Satisfaction Scale (KMS)
Time frame: Baseline (T0), 6 weeks (T1), 18 weeks (T2)
Family resilience
Walsh Family Resilience Scale (WFRS)
Time frame: Baseline (T0), 6 weeks (T1), 18 weeks (T2)
Family functioning
McMaster Family Assessment Device (FAD)
Time frame: Baseline (T0), 6 weeks (T1), 18 weeks (T2)
Intervention acceptability
A 4-item self-reported program evaluation measured on a 10-point scale, assessing: (a) easiness of the program contents, (b) usefulness of the treatment, (c) overall satisfaction, and (d) likelihood to recommend the treatment to others. Higher scores indicate greater acceptability.
Time frame: Assessed at T1 (immediately post-intervention)
No study locations are listed for this record.
Plan to share: No — The data supporting the findings of this study are available upon request from the principal investigator, Prof. Kwok. These data are not publicly available, as they contain information that could compromise the privacy of research participants.
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.