An observational study in Postoperative Complications, sponsored by St. Anne's University Hospital Brno, Czech Republic. Recruiting at 2 sites in Czechia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-05-15.
Sponsored by St. Anne's University Hospital Brno, Czech Republic · Observational
Cardiopulmonary exercise testing (CPET) is considered to be a gold standard in pre-operative risk assessment and stratification of high risk patients scheduled for major surgery. Surprisingly, only a limited number of studies examined the prognostic role of CPET in cardiothoracic surgery. This is in contrast with rather poor discriminating quality of cardiovascular surgery risk scores and predominantly elderly cardiovascular surgery patients, with significant comorbidity and high degree of frailty. Recently, CPET was shown feasible in coronary artery bypass grafting surgery candidates. Additionally, the rest parameter, which is the partial pressure of end-tidal carbon dioxide (PETCO2) and a submaximal exercise parameter (the VE/VCO2 slope) with good prognostic utility across multiple respiratory exchange ratio values), has been shown to predict mortality and post-operative complications.
Whether these rest and submaximal exercise parameters can be used to predict postoperative complications in cardiovascular surgery patients is yet to be determined.
1,233 studies on the registry are indexed under Postoperative Complications; 292 are open to participants now.
This study's planned enrollment of 130 is below the median of 254 across 519 observational studies indexed under Postoperative Complications.
Browse Postoperative Complications studies →St. Anne's University Hospital Brno, Czech Republic is the lead sponsor of 24 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients scheduled for coronary artery bypass graft surgery
Exclusion Criteria:
patients scheduled for CABG surgery will undergo pre-operative cardiopulmonary exercise testing and post-operative complications monitoring
Diagnostic Test: Cardiopulmonary exercise testing
Subjects will undergo pre-operative cardiopulmonary exercise testing.
post-operative pulmonary complications
pneumonia, atelectasis, respiratory failure, ARDS
Time frame: within 30 post-operative days
post-operative cardiovascular complications
new arrhythmias (atrial fibrillation, supraventricular tachycardia, etc.), myocardial infarction/minimal myocardial lesion, hypotension, heart failure, pulmonary edema, pulmonary embolism, cardiopulmonary resuscitation
Time frame: within 30 post-operative days
Hospital and Intensive care length of stay
Hospital and Intensive care length of stay
Time frame: within 30 post-operative days
Plan to share: Undecided — Information will be provided upon reasonable request.
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St. Anne's University Hospital Brno, Czech Republic