An interventional study of Music video game in Schizophrenia Disorders, sponsored by University of Maryland, Baltimore. Recruiting at 2 sites in United States. Open to participants aged 15 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-02-20.
Sponsored by University of Maryland, Baltimore · Not applicable, Interventional, and Basic science
Schizophrenia spectrum disorders are associated with impairment in the microstructure of white matter, the key brain tissue responsible for fast communication between different brain regions necessary for any complex task. This white matter impairment is linked to problems with cognition in schizophrenia, especially slower processing speed. This project aims to study the potential for correcting white matter deficits in schizophrenia by examining mechanisms underlying white matter structure changes in response to training on playing a mock musical instrument.
3,470 studies on the registry are indexed under Schizophrenia; 471 are open to participants now.
This study's planned enrollment of 36 is below the median of 70 across 2,871 interventional studies indexed under Schizophrenia.
Browse Schizophrenia studies →University of Maryland, Baltimore is the lead sponsor of 687 studies on the registry; 130 are open to participants now.
Of its 90 completed or terminated interventional studies of FDA-regulated products, 63 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Training sessions involving playing the video game 'Guitar Hero'
Behavioral: Music video game
Behavioral: Music video game
The video game \'Guitar Hero\' will be used as the platform for training for participants to acquire a new \'skill\'
White matter microstructure
fractional anisotropy of white matter tracts as assessed with diffusion tensor imaging
Time frame: 3 weeks
Brain level of N-acetylaspartate
NAA levels in motor cortex of brain as measured with magnetic resonance spectroscopy
Time frame: 3 weeks
Plan to share: No
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University of Maryland, Baltimore