An observational study in Tracheal Stenosis and Subglottic Stenosis, sponsored by University of Maryland, Baltimore. Recruiting at 1 site in United States. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2025-12-02.
Sponsored by University of Maryland, Baltimore · Observational
Among 11 studies in Tracheal Stenosis with a site in United States — 7 open to participants now, 7 under way, none of them phase 3. Tracheal Stenosis · United States.
Among the 11 studies in Tracheal Stenosis with a site in United States, this one is one of 2 that started in 2025, is one of 5 observational ones, and was the 10th registered.
42 studies on the registry are indexed under Tracheal Stenosis; 11 are open to participants now.
This study's planned enrollment of 10 is below the median of 76 across 15 observational studies indexed under Tracheal Stenosis.
Browse Tracheal Stenosis studies →7 of the 11 studies in Tracheal Stenosis with a site in United States are open now, in 1 country. Each count lists the studies.
Of the 8 Tracheal Stenosis studies recruiting now, 6 (75%) set no upper age limit and 0 (0%) stop at 75 or younger; 3 take children under 18; 0 take healthy volunteers.
This study: 18 Years to 80 Years · all sexes · no healthy volunteers.
The full table on the hub →11 studies; the count open now beside each. This study's row is marked.
First in 2008; this study’s year is marked. 2 started in 2025.
Median enrollment 28 across the 6 interventional studies, 100 across the 5 observational. Of the 4 that completed or were terminated, 1 (25%) have results posted.
2 of 11 have an industry lead sponsor. The 8 most frequent:
University of Maryland, Baltimore is the lead sponsor of 700 studies on the registry; 132 are open to participants now.
Of its 92 completed or terminated interventional studies of FDA-regulated products, 66 (72%) have results posted.
University of Maryland, Baltimore has 2 studies filed under Tracheal Stenosis — fewer than ten, so there is no comparison to draw.
2 of the studies in Tracheal Stenosis with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06085209Virginia Commonwealth UniversityCryospray Therapy for Benign Airway Stenosis | 2026-12-30 |
| NCT07191860Airiver Medical, Inc.Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis | 2027-11-01 |
Among the 11 studies in Tracheal Stenosis with a site in United States, from their registry updates:
Benign tracheal stenosis is a rare but potentially life-threatening condition, typically resulting from fibroinflammatory scarring. It can be secondary to iatrogenic etiologies such as intubation or tracheostomy , as well as autoimmune diseases and being idiopathic. Patients typically undergoes endoscopic or surgical interventions to open up the airways. This project will analyze resected or biopsied tissue from patients with benign tracheal stenosis to define disease-specific RNA expression profiles.
patients with benign tracheal stenosis, including idiopathic, iatrogenic, autoimmune.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Procedure: Biopsy or surgery
The tissue will be obtained from biopsy or surgical resection. All the "intervention" will be performed for clinical needs. The tissue used in the study will be considered as discarded tissue
RNA profile
The diseased mucosa will show a increased fibrosis and inflammation profile compared with that from normal mucosa
Time frame: 1 year
Plan to share: Undecided
No publications or documents are linked to this record.
Started Sep 2025 (actual). Primary completion is estimated for Sep 2026, 11 months after the start.
How these figures are worked out, and which studies are left out of them.
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Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
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University of Maryland, Baltimore →