An observational study in COPD and Ultrasound Therapy; Complications, sponsored by Assiut University. Not yet recruiting. Open to male participants aged 41 Years to 70 Years. Per ClinicalTrials.gov, last updated 2024-10-10.
Sponsored by Assiut University · Observational
There is a limited data about the association between spirometry, diaphragmatic excursion and skeletal muscle mass in patients with chronic obstructive pulmonary disease and further studies are needed
2,592 studies on the registry are indexed under Lung Diseases, Obstructive; 198 are open to participants now.
This study's planned enrollment of 64 is below the median of 150 across 639 observational studies indexed under Lung Diseases, Obstructive.
Browse Lung Diseases, Obstructive studies →Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Two groups will be enrolled in the study; the first group will include healthy volunteers who aged ≥ 40 years\& the second group will include stable COPD Patients of the same age group
Group A (control group):
Group B (study group):
Exclusion Criteria:
Group A (control group):
Patients with disorders that may affect diaphragmatic function as
Group B (study group):-
Patients with disorders that may affect diaphragmatic function as
This group include healthy volunteers who aged ≥ 40 years .
Device: ultrasound, spirometry
This include stable COPD Patients who will be diagnosed by GOLD 2024 and last excerbation ≥ 6weeks .
Device: ultrasound, spirometry
Ultrasound assessment of 1. diaphragmatic excursion:-the probe will be angled medially ,cranially , and dorsally so that the ultrasound beam reaches the posterior third of the diaphragm, in B-mode.Then, then M-mode exploration line will be placed perpendicular to the diaphragmatic dome to obtain maximum excursion . 2. (Tdi) will be measured using a high-frequency linear probe (10 MHz) placed on (ZA).The probe will be angled perpendicular to the lateral chest wall and placed between the midaxillary and anterior axillary lines at the eighth or ninth intercostal space. 3. Quadricep\|rectus femoris muscle assessment will be done by placing the transducer perpendicular to the long axis of the thigh. * Spirometry:-will be performed thrice by experienced technicians at our pulmonary function laboratory. Patients will be asked to take a maximal inspiration and then to forcefully expel air for as long and as quickly as possible.
to study the correlation between diaphragmatic excursion and FEV1
In the COPD group,The aim is to assess the correlation between diaphragmatic excursion and FEV1
Time frame: Day 1
correlation between diaphragmatic muscle function , skeletal muscle mass and duration of hospital stay
correlation between diaphragmatic excursion measured by thoracic ultrasound in cm , quadriceps muscle thickness measured by ultrasound in cm and duration of hospital stay (in days)
Time frame: Day 1
No study locations are listed for this record.
Plan to share: No
This study is not yet recruiting, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.
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Assiut University