An observational study in Bruxism, sponsored by Yuzuncu Yıl University. Not yet recruiting. Per ClinicalTrials.gov, last updated 2024-10-04.
Sponsored by Yuzuncu Yıl University · Observational
The effects of the hormones melatonin and cortisol, which play a highly effective role in regulating the sleep-wake cycle, on teeth grinding will be scientifically evaluated. Based on the research results, more effective methods for treating patients suffering from bruxism may be identified.
151 studies on the registry are indexed under Bruxism; 39 are open to participants now.
This study's planned enrollment of 100 is above the median of 89 across 55 observational studies indexed under Bruxism.
Browse Bruxism studies →Yuzuncu Yıl University is the lead sponsor of 124 studies on the registry; 7 are open to participants now.
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ndividuals with and without bruxism
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Exclusion Criteria:
Evaluation of Melatonin and Cortisol Levels in Individuals with Bruxism
Diagnostic Test: The investigation of melatonin and cortisol levels in the saliva
Evaluation of Melatonin and Cortisol Levels in Individuals without Bruxism
Diagnostic Test: The investigation of melatonin and cortisol levels in the saliva
In the related study, patient data from individuals who visited the Oral and Maxillofacial Radiology clinic at Van Yüzüncü Yıl University Faculty of Dentistry with complaints of bruxism will be used. The diagnosis of bruxism will be made based on clinical data. Diagnoses will be made by Dr. Sema KAYA using clinical findings such as patient history used for the current diagnosis of bruxism, tooth wear, tooth mobility, pain in the temporomandibular joint (TMJ), headaches, pain in the chewing muscles, hypertrophy, and a feeling of fatigue. Before taking the saliva samples, patients will be asked to rinse their mouths with sterile water, and then they will be asked to spit into sterile plastic containers. After approximately 3 mL of saliva is collected, it will be transferred to appropriate Eppendorf tubes and stored at -80°C. Melatonin and cortisol levels will later be analyzed using the enzyme-linked immunosorbent assay (ELISA) method.
levels of melatonin
individuals with bruxism
Time frame: Baseline assessment at the start of the study, follow-up assessments at 3 months and 6 months, with final data collection at 12 months.
levels of cortisol
individuals with bruxism
Time frame: Baseline assessment at the start of the study, follow-up assessments at 3 months and 6 months, with final data collection at 12 months.
No study locations are listed for this record.
Start is estimated for Oct 2024; primary completion for Dec 2024, 2 months later.
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This study is not yet recruiting, as verified in Oct 2024. You cannot join it, but the record below documents what was studied.
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