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CompletedNCT06617403ERICAUpdated May 13, 2026

Pre-operative Characteristics for Prediction of Supraglottic Airway Failure Using Machine Learning (ERICA)

An observational study in Anesthesia, General, Postoperative Complications and Laryngeal Masks, sponsored by University Hospital Ulm. Completed at 2 sites in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-13.

Sponsored by University Hospital Ulm · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
44,000
Ages
18 Years and older
Sex
All
01

Study summary

Supraglottic airway devices (SGA) are a safe and well-established technique for airway management. Nowadays, up to 60% of general anaesthetics performed in European countries use SGA. In 0.2-4.7% SGA fail and require conversion to tracheal tubes.

The ERICA study will use artificial intelligence methods to develop a model that can predict the risk of an unplanned SGA conversion based on pre-operative characteristics available during the premedication visit.

Read the detailed description

An intraoperative change of procedure not only leads to time delays but also time delays, but also involves measures that are stressful for the patient, such as deepening the anaesthesia and manipulating the airway again.

Therefore, the objective of ERICA is to develop a machine learning algorithm based on preoperative information 1) that can accurately predict the risk of an unplanned SGA conversion and 2) identifies characteristics leading to conversion from SGA to tracheal tube.

I. Developing the model

  • The final dataset will be split in a training, testing, and validation cohort. Five models will be created to predict intraoperative conversion from SGA to tracheal tube including generalized linear models (GLM), deep learning, distributed random forest (DRF), xgboost and gradient boosting machine (GBM). Then, a stacked ensemble model will be constructed through combination of the five models. Finally, the best artificial intelligence model will be chosen.

II. Identify characteristics leading to the airway conversion and categorisation.

  • Intraoperative changes of the patient's position can alter the risk of conversion, therefore operations with positional changes should be considered
  • Identify patient- and procedure-dependent characteristics that lead to conversion from SGA to tracheal tube and their importance.
02

Conditions studied

  • Anesthesia, General
  • Postoperative Complications
  • Laryngeal Masks
  • Treatment Failure

Keywords

  • "Neural Networks, Computer Artificial Intelligence"[Mesh]
  • "Laryngeal Masks"[Mesh]
  • "Treatment Failure"[Mesh]
  • "Treatment Outcome"[Mesh]
  • "Risk Factors"[Mesh]
03

In context

Postoperative Complications

1,332 studies on the registry are indexed under Postoperative Complications; 311 are open to participants now.

This study's enrollment of 44,000 is above the median of 251 across 537 observational studies indexed under Postoperative Complications.

Browse Postoperative Complications studies →

Lead sponsor

University Hospital Ulm is the lead sponsor of 10 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients (≥18 years) receiving non-cardiac surgery using a supraglottic airway device

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adult patients (≥18 years) receiving general anaesthesia for non-cardiac surgery with a supraglottic airway device

Exclusion criteria

Exclusion Criteria:

  • None
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
44,000 participants (actual)
Patient registry
No

Interventions

  • Othernon

    non

06

What researchers measure

Primary outcomes

  1. Risk of unplanned SGA conversion

    Time frame: intraoperative

07

Study locations

2 sites
  • University Hospital Ulm
    Ulm, Baden-Wurttemberg 89073, Germany
  • Technical University Munich
    Munich, Bavaria 81675, Germany
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 13, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06617403
Lead sponsor
University Hospital Ulm
Responsible party
Flora Scheffenbichler (Dr. med., University Hospital Ulm) — Principal investigator
First posted
Sep 27, 2024
Start date
Dec 1, 2022
Primary completion
Nov 30, 2024
Completion
Dec 31, 2024
Last update
May 13, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.

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