An observational study in Anterior Cruciate Ligament Rupture, sponsored by Peking University Third Hospital. Recruiting at 1 site in China. Open to participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2025-02-12.
Sponsored by Peking University Third Hospital · Observational
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Among 33 studies in Anterior Cruciate Ligament Injuries by Peking University Third Hospital — 11 open to participants now, 12 under way, none of them phase 3. Anterior Cruciate Ligament Injuries · Peking University Third Hospital.
Among the 33 studies in Anterior Cruciate Ligament Injuries by Peking University Third Hospital, this one has the largest planned enrollment of the 14 observational ones that give a count, is one of 3 that started in 2024, is one of 14 observational ones, reaches primary completion later than 2 of the 11 other live ones, and was the 26th registered.
625 studies on the registry are indexed under Anterior Cruciate Ligament Injuries; 192 are open to participants now.
Browse Anterior Cruciate Ligament Injuries studies →11 of the 33 studies in Anterior Cruciate Ligament Injuries by Peking University Third Hospital are open now, in 1 country. Recruiting first, the newest first:
Peking University Third Hospital · Sites in China
Ages 18–45 · Healthy volunteers
Peking University Third Hospital · Sites in China
Ages 18–45 · Healthy volunteers
Peking University Third Hospital · Sites in China
Ages 18–40
Peking University Third Hospital · Sites in China
Ages 18–45
Peking University Third Hospital · Sites in China
Ages 18+
By country, each count listing its studies:
Of the 122 Anterior Cruciate Ligament Injuries studies recruiting now, 27 (22%) set no upper age limit and 92 (75%) stop at 75 or younger; 46 take children under 18; 21 take healthy volunteers.
This study: 18 Years to 45 Years · all sexes · no healthy volunteers.
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33 studies; the count open now beside each. This study's row is marked.
First in 2003; this study’s year is marked. 3 started in 2024.
This study's planned enrollment of 361 is above the median of 98 across 153 observational studies indexed under Anterior Cruciate Ligament Injuries.
Median enrollment 84 across the 19 interventional studies, 115 across the 14 observational. Of the 4 that completed or were terminated, 0 (0%) have results posted.
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Peking University Third Hospital is the lead sponsor of 755 studies on the registry; 276 are open to participants now.
5 of the studies in Anterior Cruciate Ligament Injuries by Peking University Third Hospital that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06961292Peking University Third HospitalThe Clinical Efficacy of Anterolateral Complex Augmentation in Patients With ACL Rupture Combined With Excessive Internal Tibial Rotation Subluxation: A Bidirectional Cohort Study | 2026-12-31 |
| NCT07243860Peking University Third HospitalNeuromuscular Rehab for ACL Reconstruction: Knee Function & Brain Plasticity | 2027-03 |
| NCT07904949Peking University Third HospitalEffect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Recovery Quality in Patients Undergoing Anterior Cruciate Ligament Reconstruction | 2027-06-01 |
| NCT07833189Peking University Third HospitalMotor Imagery-Enhanced Rehabilitation Modulates Cortical Plasticity and Functional Recovery After ACL Reconstruction | 2027-08-10 |
| NCT07306221Peking University Third HospitalEffect of Visual-Guided Balance Training on Knee Motor Function and Biomechanical Characteristics After ACL Reconstruction | 2027-08-31 |
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Among the 33 studies in Anterior Cruciate Ligament Injuries by Peking University Third Hospital, from their registry updates:
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The aim of this study is to compare the knee function between patients with and without preoperative exercise habits at 1, 2 and 5 years after ACL surgery, and further analyze the effect of maintaining exercise habits on knee function and recurrence rate
Objective:
Methods: This is a single-center, controlled follow-up cohort study. Inclusion criteria included patients aged 18-45 years with confirmed ACL injury who were scheduled to undergo ACL reconstruction surgery. Exercise habits were recorded before operation, and knee joint function and exercise level were evaluated by questionnaires. All patients received standardized ACL reconstruction surgery and rehabilitation program after surgery. In prospective cohort study, 121 patients were divided into running group and non-running group according to their preoperative exercise habits. At 3 months after surgery, running was included in the rehabilitation program, and the patients were further divided into postoperative running and non-running groups and followed up for one year.In Postoperative cohort study， follow-up was collected and evaluated at 1 year, 2 years and 5 years, including knee function, exercise level and recurrence. The study was divided into four groups: preoperative running group , preoperative non-running group , preoperative and postoperative running group and preoperative non-running and postoperative running group to analyze the effects of preoperative and postoperative exercise habits on knee joint function and recurrence rate. The results of this study will help to deepen the understanding of the impact of preoperative exercise habits and postoperative exercise maintenance on knee function and recurrence rate after ACL reconstruction, and then provide guidance for clinical practice, optimize postoperative rehabilitation programs, and ultimately improve the quality of life of patients.
Subjects: Patients with anterior cruciate ligament rupture in Department of Sports Medicine, Peking University Third Hospital 1.1.1 Inclusion criteria
Patients were diagnosed with anterior cruciate ligament injury and planned to undergo anterior cruciate ligament reconstruction surgery 1.1.2 Exclusion criteria Presence of other severe knee disorders (e.g., arthritis).
An ACL injury was diagnosed and an ACL reconstruction surgery was planned
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Moderate-intensity aerobic exercise or strength training was performed at least 3 times per week for 6 months before surgery.
Other: no intervention
There was no regular exercise habit for 6 months before surgery
Other: no intervention
Moderate-intensity aerobic exercise was continued at least three times per week after surgery
Other: no intervention
Did not maintain a regular exercise habit after surgery
Other: no intervention
no intervention
Lysholm knee score
Time frame: 1year，2year，5year
IKDC score
Time frame: 1year，2year，5year
Tegner score
Time frame: 1year，2year，5year
Beighton Score
Time frame: 1year，2year，5year
recurrence rate
Time frame: 1year，2year，5year
Plan to share: No
No publications or documents are linked to this record.
Started Nov 2024 (actual). Primary completion is estimated for Dec 2025, 13 months after the start.
Of 73 non-industry observational studies under Anterior Cruciate Ligament Injuries, half reached primary completion within 36 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 167. This study's planned 13 months is below that.
Counting every sponsor, half of 82 studies reached it within 37 months; a quarter within 13 and three quarters within 76.
How these figures are worked out, and which studies are left out of them.
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