An interventional study of Group 1: LEE in Post Induction Hypotension, sponsored by The University of Texas Health Science Center, Houston. Completed at 1 site in United States. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-02-24.
Sponsored by The University of Texas Health Science Center, Houston · Not applicable, Interventional, and Prevention
The purpose of this study is to determine if lower extremity elevation (LEE) will reduce the incidence of postinduction hypotension, to compare the utilization of vasoactive medications after induction in patients with LEE and patients without LEE and to determine if LEE will increase measured cardiac output
1,003 studies on the registry are indexed under Hypotension; 173 are open to participants now.
This study's enrollment of 200 is above the median of 80 across 675 interventional studies indexed under Hypotension.
Browse Hypotension studies →The University of Texas Health Science Center, Houston is the lead sponsor of 880 studies on the registry; 209 are open to participants now.
Of its 170 completed or terminated interventional studies of FDA-regulated products, 140 (82%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Procedure: Group 1: LEE
Patients will be in supine position during induction with a 12" wedge placed at the level of the Achilles tendon (LEE)
Number of participants that demonstrate hypotension
Hypotension is defined as the reduction in mean arterial pressure by 20% or greater comparing the blood pressure measured before induction of anesthesia
Time frame: From start of anesthesia upto institution of positive pressure ventilation (about 5 minutes)
Number of participants that demonstrate Nadir blood pressure
Nadir blood pressure is the lowest value of blood pressure (BP) that can occur
Time frame: From start of anesthesia upto institution of positive pressure ventilation (about 5 minutes)
Change in heart rate
Time frame: From start of anesthesia upto institution of positive pressure ventilation (about 5 minutes)
Number of participants that need rescue vasoactive agents
Time frame: From start of anesthesia upto institution of positive pressure ventilation (about 5 minutes)
Accumulated dose of rescue vasoactive agents
Time frame: End of study (within 15 minutes of baseline)
Change in non-invasive cardiac output
Time frame: From start of anesthesia upto institution of positive pressure ventilation (about 5 minutes)
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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The University of Texas Health Science Center, Houston