An observational study in Crohn Disease, sponsored by Zagazig University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-08-17.
Sponsored by Zagazig University · Observational
crohn's disease patients who present by intestinal perforation as the first presentation are hard to deal with. Surgical techniques as anastmosis or diversion stoma and active course of the disease may greatly affect the quality of life. In post-operative period, is the priority to avoid the post operative complications and to improve surgical outcomes or to stop active course of the disease and to induce remission?. So, those patients were classified into two groups. one group received biological therapy early post operative and the other group received it 2 or 3 months later after surgery and the investigators will compare results between the two groups.
1,880 studies on the registry are indexed under Crohn Disease; 462 are open to participants now.
This study's enrollment of 60 is below the median of 162 across 608 observational studies indexed under Crohn Disease.
Browse Crohn Disease studies →Zagazig University is the lead sponsor of 447 studies on the registry; 75 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
patients with Crohn's disease presented with bowel perforation
Exclusion Criteria:
Biological: early biologic therapy
Biological: late biologic therapy
biologic therapy for perforated Crohn's disease in the early postoperative period
no biologic therapy for perforated Crohn's disease up to 2 to3 months in the post operative period
size of intra-abdominal fluids or collection
size of peritoneal fluids will be measured by surface area in centimeter square ( weight x height) using ultrasound
Time frame: from the first post-operative day to 2 months postoperatively
bowel function
bowel function will be assessed by hearing intestinal sound using Stethoscope
Time frame: from the first post-operative day to 2 months postoperatively
fecal fistula
if found, its amount will be calculated per day using calibrated colostomy bag
Time frame: from the first post-operative day to 2 months postoperatively
skin maceration
skin maceration surface area will be calculated by (weight x height) in centimeter square using a ruler
Time frame: from the first post-operative day to 2 months postoperatively
body weight
weight gain or weight loss will be measured in kg
Time frame: from the first post-operative day to 2 months postoperatively
age
age in years will be recorded
Time frame: 2 hours before surgery
sex
sex of patients (male or female) will be recorded
Time frame: 2 hours before surgery
Plan to share: No — data will be available on demand by contacting the principle investigator
No publications or documents are linked to this record.
This study is completed, as verified in Jul 2024. You cannot join it, but the record below documents what was studied.
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Zagazig University