An interventional study of Kiss in Dental Caries, Tooth Demineralization and Teeth Erosion Limited to the Enamel, sponsored by Universidad Catolica Santiago de Guayaquil. Completed at 1 site in Ecuador. Open to participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-04-24.
Sponsored by Universidad Catolica Santiago de Guayaquil · Not applicable, Interventional, and Prevention
The pH of saliva can be acidic or alkaline; When it is acidic, the tooth enamel is demineralized, that is, weakened. Additionally, bacteria in the mouth can increase and cause infections such as cavities. This occurs when we consume sugary or fermented drinks, such as soda or beer.
The intention of the research team is to give some of these drinks to the study participants and verify the decrease in salivary pH. Next, a group of people will be asked to kiss their partner on the mouth, and then the pH will be measured again to see if it increases, that is, if it stops being acidic faster than in the group that did not kiss.
The aim is to demonstrate that kissing on the mouth between two people can protect teeth from cavities by rapidly increasing the pH of saliva after it has decreased to become acidic.
The goal of this intervention study will be to determine if oral kissing between two people can increase salivary pH more quickly after drinking artificial juices, soft drinks, or (non-alcoholic) beers. It will also be studied whether the pH restoration time is faster when only one person kisses one of the named drinks or when both people do it. The main questions that are intended to be answered are the following:
Saliva pH measurements will be performed, after initiation and consumption of the drinks, every 5 minutes for up to 40 minutes. That is, until the restoration of salivary pH is ensured in all groups.
Participants:
1,171 studies on the registry are indexed under Dental Caries; 209 are open to participants now.
This study's enrollment of 33 is below the median of 60 across 967 interventional studies indexed under Dental Caries.
Browse Dental Caries studies →Universidad Catolica Santiago de Guayaquil is the lead sponsor of 4 studies on the registry; 2 are open to participants now.
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Exclusion Criteria:
The couples in the control group will not kiss; they will only wait for the salivary pH to neutralize physiologically.
the group in which only one person in the couple consumes the sugary or fermented drink and they kiss
Other: Kiss
In this group, both people will consume the drinks and then kiss.
Other: Kiss
Participants will kiss with their partners for 40 seconds. The kiss will be on the mouth.
salivary pH
It is expected to measure the progressive increase in pH until reaching a neutral point, which occurs physiologically between 30 to 40 minutes, and compare the time spent by the control group with that of the experimental group. Measurements will be taken every 5 minutes from the kiss, which will last 40 seconds. In total, there will be 8 measurements, not counting the initial one for surveying the baseline. The measurement will be carried out with a calibrated pH meter. People will be asked to drool into a test tube
Time frame: In a period of every 5 minutes, until reaching 40 minutes, which is the time in which physiologically the pH of the saliva is neutralized.
Plan to share: Undecided
Ran from Jul 2024 to primary completion in Feb 2025, 6 months.
Of 469 non-industry interventional studies with no phase under Dental Caries, half reached primary completion within 15 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 30. This study's 6 months is below that.
Counting every sponsor, half of 502 studies reached it within 15 months; a quarter within 7 and three quarters within 29.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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Universidad Catolica Santiago de Guayaquil