An interventional study of Root canal treatment with AH Plus sealer and Root canal treatment with BioCeramic sealer in Periapical Lesions, sponsored by Damascus University. Completed at 1 site in Syrian Arab Republic. Open to participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-05-06.
Sponsored by Damascus University · Not applicable, Interventional, and Treatment
This clinical study will evaluate the effect of BioCeramic sealer with single cone compared with the control group treated with AH Plus with lateral condensation in root canal obturation on the healing of periapical lesions.
The study sample will consist of 41 patients with 65 teeth with clear periapical lesions.
Root canal obturation will be applied for all patients. BioCeramic sealer will be applied for the experimental group only.
The changes of the dimensions of the periapical lesion will be assessed using CBCT radiographs; pre- and post- treatment changes for each group will be evaluated individually.
Periapical lesions is considered as the most common symptoms associated with infected root canals.
Recently, the BioCeramic sealer has been considered one of the most common endodontic sealer that possess antibacterial properties, so it can have an effective role in the healing of periapical lesions, as well as its ability to prevent periapical leakage due to its attachment to the dentinal walls and gutta-percha cones.
This study will evaluate the effect of BioCeramic sealer on the healing of periapical lesions and the changes of the dimensions of the lesions.
Root canal obturation with gutta-percha cones will be applied in the two groups: The control group will receive the AH Plus with lateral condensation technique, and the experimental group will receive BioCeramic sealer with single cone technique.
CBCT radiographs will be gotten before and after one year of the treatment to evaluate the periapical lesion dimensions changes.
Damascus University is the lead sponsor of 206 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
in this group, root canal system was filled with AH Plus sealer in conjunction with lateral condensation.
Procedure: Root canal treatment with AH Plus sealer
in this group, root canal system was filled with BioCeramic-based sealer in conjunction with single gutta-percha cone.
Procedure: Root canal treatment with BioCeramic sealer
- AH Plus sealer Group: the base and accelerator of AH Plus Sealer was mixed, then the walls of the canal were coated with the AH Plus sealer using K-File, then lateral condensation was performed through a number of gutta-percha cones.
- BioCeramic Sealer Group: the canals in this group were filled using BioCeramic-based sealer and a single gutta-percha cone, and gently insert it into the root canal to the preselected working length without applying pressure.
Change in the periapical lesion diameter
This diameter of the periapical lesions is going to be measured on a CBCT image. Initially, the sections of the periapical lesions will be evaluated in the three planes (sagittal, coronal, and axial). The section that contains the largest area of the lesion in each studied plane, will be used for measurement. * If the shape of periapical lesion is circular, the periapical diameter would be taken (at this plane) relying on the scale in the program accompanying the radiograph (CBCT). * If the shape of periapical lesion is not circular, the largest and smallest diameter of the lesion will be taken (at this plane) depending on the scale in the program accompanying the CBCT image, then the mean diameter will be calculated by collecting the previous two diameter and dividing them by 2. Ultimately, the three diameters of the lesion (taken at the three planes) are collected and the total is divided into 3 to obtain the mean diameter of the lesion.
Time frame: before and after one year of the treatment (root canal obturation)
Change in the presence of edema
The detection of the edema will be performed using clinical examination (palpating the buccal tissues of the treated tooth). Time Frame: before, after six months, and after one year of the treatment (root canal obturation)
Time frame: before, after six months, and one year of the treatment (root canal obturation)
This study is completed, as verified in May 2024. You cannot join it, but the record below documents what was studied.
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Damascus University