An observational study in Meningioma, sponsored by Central Hospital, Nancy, France. Enrolling by invitation. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-02-26.
Sponsored by Central Hospital, Nancy, France · Observational
This research aims to explore the relationship between hormonal receptor expression and the clinical and histopathological characteristics of meningiomas. The underlying hypothesis is that hormonal receptor expression, as well as the methylation profile of their gene promoters, are associated with specific aspects of meningiomas and patients' clinical outcomes. The main objective is to study the correlation between the immunohistochemical expression of hormonal receptors and clinicopathological data. The secondary objectif is to study the correlation between the methylation profile of hormonal receptor gene promoters and their immunohistochemical expression.
226 studies on the registry are indexed under Meningioma; 87 are open to participants now.
This study's planned enrollment of 180 is above the median of 132 across 56 observational studies indexed under Meningioma.
Browse Meningioma studies →Central Hospital, Nancy, France is the lead sponsor of 778 studies on the registry; 183 are open to participants now.
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Patients who underwent surgery for a meningioma at the University Hospital of Nancy between 2000 and 2022.
Exclusion Criteria:
immunohistochemical expression of different hormonal receptors
Evaluated on FFPE sections
Time frame: up to 24 years after surgery
methylation profile of the promoters of hormonal receptor genes
Methylation profile established from frozen tissue.
Time frame: up to 24 years after surgery
No study locations are listed for this record.
Plan to share: Undecided
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Central Hospital, Nancy, France