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CompletedNCT06252246Updated Feb 9, 2024

The Effect of Phacoemulsification on Intraocular Pressure in Primary Angle Closure Glaucoma (PACG) Patients At Phanat Nikhom Hospital, Chonburi Province

An observational study in Primary Angle Closure Glaucoma, sponsored by Phanatnikhom Hospital. Completed at 1 site in Thailand. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-02-09.

Sponsored by Phanatnikhom Hospital · Observational

Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
121
Ages
18 Years and older
Sex
All
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Study summary

BACKGROUND: Primary angle closure glaucoma (PACG) is one of a leading cause of blindness worldwide including Thailand. This problem impact to the overall health of people and health care system. Treatment guidelines of each stage is differenced. Therefore, factors that affect to treatment should be explored to plan for taking care patients in the future.

OBJECTIVES: The study aimed to examine the effects of cataract surgery by phaco- emulsification on intraocular pressure and to determine the factors associated with intraocular pressure among primary angle closure glaucoma patients.

Read the detailed description

BACKGROUND: Primary angle closure glaucoma (PACG) is one of a leading cause of blindness worldwide including Thailand. This problem impact to the overall health of people and health care system. Treatment guidelines of each stage is differenced. Therefore, factors that affect to treatment should be explored to plan for taking care patients in the future.

OBJECTIVES: The study aimed to examine the effects of cataract surgery by phaco- emulsification on intraocular pressure and to determine the factors associated with intraocular pressure among primary angle closure glaucoma patients.

METHODS: A retrospective descriptive study was conducted in 121 patients with primary angle closure glaucoma who underwent phacoemulsification between October 1st 2017 and September 30th 2022. The preoperative and postoperative record form were used as the research instrument. Visual acuity, intraocular pressure, the number of glaucoma medications and ocular biometric parameters were collected. The descriptive statistics, Paired sample t-test, Repeated measures ANOVA and Multiple linear regression were used to analyze the outcomes. A p-value \< 0.05 was considered statistically significant.

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Conditions studied

  • Primary Angle Closure Glaucoma
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In context

Glaucoma, Angle-Closure

91 studies on the registry are indexed under Glaucoma, Angle-Closure; 17 are open to participants now.

This study's enrollment of 121 is below the median of 225 across 32 observational studies indexed under Glaucoma, Angle-Closure.

Browse Glaucoma, Angle-Closure studies →

Lead sponsor

This is the only study on the registry with Phanatnikhom Hospital as lead sponsor.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Primary angle closure glaucoma (PACG) is one of a leading cause of blindness worldwide including Thailand. This problem impact to the overall health of people and health care system. Treatment guidelines of each stage is differenced. Therefore, factors that affect to treatment should be explored to plan for taking care patients in the future

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • age more 18 years old and not complication of cataract surgey

Exclusion criteria

Exclusion Criteria:

  • other eye diseases affect to visual defect
  • previous ocular surgery
  • complication of cataract surgery
  • data record incomplete
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Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
121 participants (actual)
Patient registry
No

Interventions

  • DevicePhacoemulsification machine

    type of phacoemulsification machine is different

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What researchers measure

Primary outcomes

  1. intraocular pressure

    effects of cataract surgery by phacoemulsification on intraocular pressure and to determine the factors associated with intraocular pressure among primary angle closure glaucoma patients. Units of measure assessment intraocular pressure by non contact tonometry(intraocular pressure in millimeters of Mercury) at one week, one month, three months and six months postoperatively

    Time frame: six months

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Study locations

1 site
  • Phanatnikhom hospital
    Chon Buri, Chonburi 20140, Thailand
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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 9, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06252246
Lead sponsor
Phanatnikhom Hospital
Responsible party
Thetthar Kanthar (Head of Ophthalmology, Ophthalmological department, Phanatnikhom Hospital) — Principal investigator
First posted
Feb 9, 2024
Start date
Oct 1, 2017
Primary completion
Sep 30, 2022
Completion
Sep 30, 2022
Last update
Feb 9, 2024

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.

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