An observational study in Pain, Acute, Postoperative Pain and Hip Fractures, sponsored by Ondokuz Mayıs University. Completed at 1 site in Turkey. Open to participants aged 50 Years to 85 Years. Per ClinicalTrials.gov, last updated 2025-02-24.
Sponsored by Ondokuz Mayıs University · Observational
Hip fractures are morbid conditions, especially in elderly patients, and their treatment is usually surgical. Pericapsular nerve group block targets the hip capsule. The aim of this study is to investigate and compare the perioperative analgesic efficacy of PENG blocks applied investigation of the effect of perinuerally and systemic dexamethasone on pain scores in the first 24 hours of PENG block in patients undergoing hip fracture surgery under spinal anesthesia.
Hip fractures are morbid conditions, especially in elderly patients, and their treatment is usually surgical. Pericapsular nerve group block targets the hip capsule. The aim of this study is to investigate and compare the perioperative analgesic efficacy of PENG blocks applied investigation of the effect of perinuerally and systemic dexamethasone on pain scores in the first 24 hours of PENG block in patients undergoing hip fracture surgery under spinal anesthesia.
44 ASA II-IV patients between 50-80 years of age who will be operated for femoral neck fractures will be included in the study.
PENG block is routinely used in our clinic to provide postoperative analgesia in hip surgery. Depending on the comorbid conditions of the patients, dexamethasone may be added as an adjuvant agent to improve the quality of the block. We aimed to observe the systemic and perinuerally effects of dexamethasone used in PENG block in patients operated for femoral neck fracture in our clinic.
In this observational and prospective study, patients operated for femoral neck fracture and treated with PENG block will be analyzed in the postoperative period. Pain scores, degree of nausea and vomiting, recovery time of sensory and motor block, and blood glucose levels in the first 24 hours will be recorded in patients who received dexamethasone perinuerally and in patients who received systemic dexamethasone intravenously. In addition, the time to first analgesic requirement, mobilization time and hospital stay of the two groups will also be recorded.
The anesthesiologist performing the block will not participate in the pain monitoring of the patients. Postoperative pain assessment and data collection will be performed by another anesthesiologist blinded to the study. For the quality and standardization of the block, the block will be performed by an experienced anesthesiologist who has performed the block successfully and without complications at least 20 times before.
822 studies on the registry are indexed under Hip Fractures; 160 are open to participants now.
This study's enrollment of 44 is below the median of 140 across 268 observational studies indexed under Hip Fractures.
Browse Hip Fractures studies →Ondokuz Mayıs University is the lead sponsor of 262 studies on the registry; 68 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients aged 50-85 years who underwent surgery for femoral neck fracture and underwent PENG block
Exclusion Criteria:
Ultrasound guided PENG block with perinuerally dexamethasone administration group
Drug: Group P
Ultrasound guided PENG block with systemic dexamethasone administration group
Drug: Group S
In this group, US guided PENG block will be performed with 20 cc 0.25% bupivacaine and 4 mg dexamethasone.
Also known as: Perinuerally
In this group, US guided PENG block will be performed with 20 cc 0.25% bupivacaine. In addition, 4 mg dexamethasone will be administered intravenously.
Also known as: Systematic
Pain scores on the Numeric Rating Scale (NRS)
Changes in Numeric Rating Scale (NRS) at rest and in activity will be recorded at intervals. At 0-6-12-24 hours, pain will be evaluated with the NRS score in two different situations. Patients will be informed about the Numeric Rating Scale used in the assessment of pain and pain intensity will be determined at rest and 24 hours postoperatively during 15 degrees passive leg raising. Patients will be asked to express their pain intensity numerically between 0 and 10, with 0 for no pain and 10 for the most severe pain.
Time frame: Postoperative 0th, 6th,12th and 24th hours
Postoperative nausea and vomiting
The severity of nausea and vomiting was determined by a four-point Verbal Descriptive Scale.
Time frame: Postoperative 6th, 12th and 24th hours
The degree of motor block
The degree of motor block will be evaluated with the Bromage scale.
Time frame: Postoperative 6th, 12th and 24th hours
The degree of sensory block
The degree of sensory block will be evaluated with the Pinprick test.
Time frame: Postoperative 6th, 12th and 24th hours
This study is completed, as verified in Feb 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Ondokuz Mayıs University