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CompletedNCT06230575Updated Nov 19, 2025

Locoregional Blocks for Breast Cancer Surgeries

An interventional study of erector spinae block and retrolaminar block in Analgesia, sponsored by National Cancer Institute, Egypt. Completed at 1 site in Egypt. Open to female participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2025-11-19.

Sponsored by National Cancer Institute, Egypt · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
188
Allocation
Randomized
Ages
18 Years to 65 Years
Sex
Female
01

Study summary

Breast surgeries are common operative procedures that require appropriate postoperative analgesia.

Read the detailed description

Numerous pain relief techniques, including several new regional anesthesia techniques, are available for control of acute pain after breast surgery.

02

Conditions studied

  • Analgesia

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03

In context

Agnosia

1,190 studies on the registry are indexed under Agnosia; 508 are open to participants now.

This study's enrollment of 188 is above the median of 78 across 1,024 interventional studies indexed under Agnosia.

Browse Agnosia studies →

Lead sponsor

National Cancer Institute, Egypt is the lead sponsor of 133 studies on the registry; 29 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • female cancer breast patient
  • age from 18- 65

Exclusion criteria

Exclusion Criteria:

  • coagulation defect
  • Patient refusal
  • abnormal kidney and or liver function tests
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
188 participants (actual)

Study arms

  • Active comparator
    erector spinae block

    Erector spinae plane block on the ipsilateral operative site

    Procedure: erector spinae block

  • Experimental
    retrolaminar block

    Retrolaminar plane block on the ipsilateral operative site

    Procedure: retrolaminar block

  • Experimental
    serratus anterior block

    Serratus anterior plane block on the ipsilateral operative site

    Procedure: serratus anterior block

  • Experimental
    pectoral nerve block II

    Pectoral nerve block II on the ipsilateral operative site

    Procedure: pectoral nerve block

Interventions

  • Procedureerector spinae block

    Erector spinae plane block

  • Procedureretrolaminar block

    Retrolaminar block

  • Procedureserratus anterior block

    Serratus anterior plane block

  • Procedurepectoral nerve block

    Pectoral nerve block

06

What researchers measure

Primary outcomes

  1. time to receive first postoperative analgesic

    time to first dose of rescue opioid analgesic

    Time frame: First 24 hours postoperatively

07

Study locations

1 site
  • Walaa Y Elsabeeny
    Cairo, 11796, Egypt
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 19, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT06230575
Lead sponsor
National Cancer Institute, Egypt
Responsible party
Walaa Youssef Elsabeeny (Assistant professor of Anesthesia, Surgical Critical care and Pain management, National Cancer Institute, Egypt) — Principal investigator
First posted
Jan 30, 2024
Start date
Feb 1, 2024
Primary completion
Oct 15, 2025
Completion
Nov 7, 2025
Last update
Nov 19, 2025

Study contacts

Walaa Y Elsabeeny, MD
principal investigator · Assistant professor of Anesthesia, Surgical critical care and Pain Management, National Cancer Institute, Cairo University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2025. You cannot join it, but the record below documents what was studied.

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