An observational study in Abdominal Surgery, Endotracheal Intubation and Surgical Incision, sponsored by Seoul National University Hospital. Completed at 1 site in South Korea. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-01-06.
Sponsored by Seoul National University Hospital · Observational
This study aims to prospectively evaluate the relationship between changes in EEG and hormonal responses induced by endotracheal intubation and surgical incision following general anesthesia.
This study aims to investigate the relationship between changes in EEG patterns and stress hormone levels in patients undergoing open abdominal surgery under general anesthesia when subjected to endotracheal intubation and surgical incision stimuli.
Hormone measurements (cortisol, ACTH) are taken at four time points: before endotracheal intubation (T1), one minute after intubation (T2), and one minute after surgical incision (T3). The investigators evaluate the correlation between hormone levels (cortisol, ACTH) and EEG band power changes (alpha, beta, delta) before and after endotracheal intubation and surgical incision.
519 studies on the registry are indexed under Surgical Wound; 71 are open to participants now.
This study's enrollment of 52 is below the median of 117 across 82 observational studies indexed under Surgical Wound.
Browse Surgical Wound studies →Seoul National University Hospital is the lead sponsor of 1,860 studies on the registry; 275 are open to participants now.
Of its 12 completed or terminated interventional studies of FDA-regulated products, 2 (17%) have results posted.
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Adult patients undergoing open abdominal surgery and endotracheal intubation under general anesthesia
Exclusion Criteria:
Inserting endotracheal tube into the trachea
Association between band power changes in EEG and hormone respones caused by endotracheal intubation
Time frame: from the start of anesthesia induction to one minute after endotracheal intubation
Association between band power changes in EEG and hormone respones caused by surgical incision
Time frame: from the start of anesthesia induction to one minute after surgical incision
This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.
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Seoul National University Hospital