An observational study in Bone Resorption, sponsored by Mansoura University. Recruiting at 1 site in Egypt. Open to participants aged 55 Years to 65 Years. Per ClinicalTrials.gov, last updated 2024-01-26.
Sponsored by Mansoura University · Observational
Studies clinically evaluate the long-term outcome of 4 implant attachment-retained mandibular OVDs among patients with high glycemic levels are lacking.
Chronic hyperglycemia is considered as a typical risk-factor that causes soft tissue inflammation and bone loss around natural teeth and implants. One possible explanation for this mechanism is that chronic hyperglycemia has the propensity to increase the levels of accumulated glycation end products (AGEs) in the serum and oral tissues that accelerates the production of proinflammatory cytokines that induce bone destruction around natural teeth and implants. However, it is relevant to indicate that dental implants in chronic hyperglycemia under ideal glycemic conditions can successfully osseointegrate and show predictable outcomes over long durations in both diabetic and non-diabetic patients.
Studies clinically evaluate the long-term outcome of 4 implant attachment-retained mandibular OVDs among patients with high glycemic levels are lacking.
167 studies on the registry are indexed under Bone Resorption; 28 are open to participants now.
This study's planned enrollment of 20 is below the median of 43 across 18 observational studies indexed under Bone Resorption.
Browse Bone Resorption studies →Mansoura University is the lead sponsor of 1,119 studies on the registry; 183 are open to participants now.
Of its 9 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
20 participants at least.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
This group represents a well-controlled type 2 Diabetics mellitus.
Other: Observational study
This group represents a poorly controlled type 2 Diabetics mellitus.
Other: Observational study
evaluate implant survival, peri-implant outcome of 4 implant retained mandibular OVD after 10 years of function.
Crestal bone loss around implants
amount of bone loss which appears on a periapical radiograph
Time frame: This is a retrospective study, Measurement will be performed after implants being in service by 10 years
Probing depth
By using a plastic periodontal probe to measure the probing depth around the implants
Time frame: This is a retrospective study, Measurement will be performed after implants being in service by 10 years
Plan to share: No — The IPD is upon request from the corresponding author
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