An observational study in Carotid Artery Stenosis, sponsored by Radboud University Medical Center. Completed at 1 site in Netherlands. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-03-21.
Sponsored by Radboud University Medical Center · Observational
Objective: To evaluate the technical performance of a novel cascaded wave imaging technique compared to plane wave imaging for blood flow imaging in patients with and without carotid artery stenosis.
Study design: Observational, feasibility study in a total of 10 patients with and 10 patients without a hemodynamic significant carotid artery plaque.
Intervention (observational): all participants will undergo a carotid ultrasound measurement including conventional duplex ultrasound and ultrasound based flow imaging using plane waves and cascaded waves.
339 studies on the registry are indexed under Carotid Stenosis; 81 are open to participants now.
This study's enrollment of 20 is below the median of 173 across 144 observational studies indexed under Carotid Stenosis.
Browse Carotid Stenosis studies →Radboud University Medical Center is the lead sponsor of 959 studies on the registry; 134 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
10 patients with and 10 patients without a hemodynamic significant carotid artery stenosis
Exclusion Criteria:
Diagnostic Test: Conventional duplex · Diagnostic Test: Ultrasound-based flow imaging using plane wave imaging · Diagnostic Test: Ultrasound-based flow imaging using cascaded wave imaging
Diagnostic Test: Conventional duplex · Diagnostic Test: Ultrasound-based flow imaging using plane wave imaging · Diagnostic Test: Ultrasound-based flow imaging using cascaded wave imaging
Conventional carotid duplex measurement
Ultrasound-based flow imaging using plane wave imaging
Ultrasound-based flow imaging using cascaded wave imaging
2D velocity vector fields obtained by plane wave and cascaded wave imaging of the carotid artery
Time frame: After study completion, average of one year
Signal-to-noise ratio obtained from plane wave and cascaded wave imaging will be obtained and compared for different vessel depths
Time frame: After study completion, average of one year
Cross-correlation maps of plane wave and cascaded wave imaging will be obtained and compared for different vessel depths
Time frame: After study completion, average of one year
Velocity vector fields obtained from plane wave and cascaded wave imaging will be obtained and compared
Time frame: After study completion, average of one year
Blood-flow related parameters, including vector complexity and vorticity, will be calculated from 2D velocity fields.
Time frame: After study completion, average of one year
Spatiotemporal blood flow profiles obtained with plane wave, cascaded wave and conventional duplex ultrasound will be compared to assess the correlation between these techniques
Time frame: After study completion, average of one year
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Nov 2024. You cannot join it, but the record below documents what was studied.
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Radboud University Medical Center