An observational study in Glaucoma, Angle-Closure, sponsored by Min Ke. Completed at 1 site in China. Open to participants aged 30 Years to 92 Years. Per ClinicalTrials.gov, last updated 2023-11-22.
Sponsored by Min Ke · Observational
The goal of this observational study is to examine the anterior segment anatomical parameters associated with the scleral spur and cornea for risk profiling of primary angle-closure glaucoma (PACG). The main question it aims to answer is:
We aimed to examine the anterior segment anatomical parameters associated with the scleral spur and cornea for risk profiling of primary angle-closure glaucoma (PACG).
This retrospective study included 84 patients with PACG and 84 patients with narrow angles (NA). We collected parametric measurements obtained using anterior-segment optical coherence tomography and IOLMaster 700. Univariate and multivariate logistic regression models were used to compare the ocular parameters between the NA and PACG groups as well as to identify risk factors for PACG. The predictive performance of each parameter was evaluated using the area under the receiver operating characteristic curve (AUROC) analysis.
91 studies on the registry are indexed under Glaucoma, Angle-Closure; 17 are open to participants now.
This study's enrollment of 168 is below the median of 225 across 32 observational studies indexed under Glaucoma, Angle-Closure.
Browse Glaucoma, Angle-Closure studies →Min Ke is the lead sponsor of 2 studies on the registry; 1 is open to participants now.
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Patients with PACG and anterior chamber angle stenosis were enrolled in this study and excluded from other diseases affecting the structure of the anterior segment of the eye, as well as a history of intraocular surgery.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
(1) severe systemic disease, (2) secondary angle-closure glaucoma, (3) other ocular diseases, (4) history of intraocular surgery, and (5) unclear examination images.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A “mini-stroke”: temporary stroke-like symptoms caused by reduced blood flow to part of the brain, spinal cord or eye, without signs of a new stroke on a scan.
Stroke symptoms need emergency care at once, even if they go away.
TIA (transient ischaemic attack)
A “mini-stroke”: temporary stroke-like symptoms caused by reduced blood flow to part of the brain, spinal cord or eye, without signs of a new stroke on a scan.
Stroke symptoms need emergency care at once, even if they go away.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Trabecular scleral-spur angle
The angle between the line of the corneal endothelium 750 μm from the scleral spur to the scleral spur and the bilateral line of the scleral spur
Time frame: 2022-11-22 to 2022-12.31
Plan to share: No
No publications or documents are linked to this record.
Ran from Nov 2022 to primary completion in Dec 2022, 1 month.
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This study is completed, as verified in Nov 2023. You cannot join it, but the record below documents what was studied.
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Min Ke