An observational study in Kidney Injury, sponsored by Assiut University. Not yet recruiting. Open to participants aged 16 Years to 80 Years. Per ClinicalTrials.gov, last updated 2023-10-31.
Sponsored by Assiut University · Observational
The aim of this study is to identify the incidence and the factors associated with acute kidney injury in adult poly trauma patients
Trauma causes significant morbidity and mortality in all age groups but particularly for those below 60 years and is one of the top 5 causes of death (1,2).Most deaths occur in adults who are between 15 and 44 years(3).Polytrauma originates from the Greek words poly which means multiple and trauma which means wounds. The term polytrauma, which was defined using the new Berlin definition, as cases with an Abbreviated Injury Scale (AIS)≥3 for two or more different body regions and one or more additional variables from five physiologic parameters (hypotension[systolic blood pressure≤90 mmHg], unconsciousness[Glasgow Coma Scale score≤8], acidosis [base excess≤ -6.0], coagulopathy [partial thromboplastin time≥40 s or international normalized ratio≥1.4], and age [≥70 years]) [4].There are complex pathophysiological changes that happen in a polyrauma patient which requires effective treatment for improving morbidity and mortality outcomes. Hemorrhage, systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) are some of the complications of trauma whose effects are not only local but also systemic. There are mechanisms and triggers which result in cardio-vascular shock, hemostasis, apoptosis, organ dysfunctions and immune suppression (CHAOS) [5]. These local and systemic pathophysiological changes that occur in polytrauma (CHAOS) eventually lead to Acute Kidney Injury (AKI) which further worsens their outcomes [6,7].
139 studies on the registry are indexed under Multiple Trauma; 32 are open to participants now.
This study's planned enrollment of 100 is below the median of 200 across 84 observational studies indexed under Multiple Trauma.
Browse Multiple Trauma studies →Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.
Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Adult polytrauma patients above 16 years old with no history of renal disease or chronic illness
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Exclusion Criteria:
Patients who are less than 16 years old.
Determine the incidence of acute kidney injury in poly trauma patients
To identify the incidence and factors associated with acute kidney injury in adult polytrauma patients
Time frame: 7 days
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This study is not yet recruiting, as verified in Oct 2023. You cannot join it, but the record below documents what was studied.
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