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CompletedNCT06100991Updated Nov 6, 2026

CorEvitas Generalized Pustular Psoriasis (GPP) Drug Safety and Effectiveness Registry

An observational study in Generalized Pustular Psoriasis, sponsored by CorEvitas. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-06.

Sponsored by CorEvitas · Observational

Updated Nov 6, 2026Now CompletedNow Active, not recruiting+3 moreGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
46
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 763 studies in Psoriasis with a site in United States — 54 open to participants now, 85 under way, 19 of them phase 3. Psoriasis · United States.

Enrollment
67th of 90
46 · median 200
Started
2023
with 31 others
Observational
90 of 763
17 open now
Registered
695th of 763
by date

Among the 763 studies in Psoriasis with a site in United States, this one is the 67th largest by enrollment of the 90 observational ones that give a count, is one of 32 that started in 2023, is one of 90 observational ones, and was the 695th registered.

Psoriasis

2,028 studies on the registry are indexed under Psoriasis; 275 are open to participants now.

Browse Psoriasis studies →

Open to participants now

54 of the 763 studies in Psoriasis with a site in United States are open now. Recruiting first, the newest first:

49 more — sign in →

All 54 open studies →

A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →

Who these studies take

Of the 174 Psoriasis studies recruiting now, 91 (52%) set no upper age limit and 67 (39%) stop at 75 or younger; 25 take children under 18; 40 take healthy volunteers.

This study: 18 Years and older · all sexes · healthy volunteers too.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 763 studies in Psoriasis with a site in United States, or all of them as a file.
02

Study summary

Prospective, observational registry for subjects with GPP under the care of a dermatology investigator.Approximately 200 subjects and 75 clinical sites in North America will be recruited to participate with no defined upper limit for either target

Read the detailed description

The objective of the registry is to obtain information on the treatment patterns, disease activity progression, and the development of comorbidities and adverse events in a cohort of patients with GPP. Data collected will be used to better characterize the natural history and longitudinal trajectory of the disease. This will be done through the standardized data collection including validated patient-reported outcomes (PRO) and clinician-reported outcomes (ClinRO), the active evaluation of prevalent and incident comorbidities and adverse events, and the recording of medication utilization patterns. Personal information is also collected from each consenting registry subject allowing for linkages to other public or private clinical and administrative databases, as well as to databases maintained by organizations focused on the care and treatment of GPP for the purposes of clinical, market, or outcomes research.

This provides an opportunity to evaluate other aspects of the disease and its treatment, including but not limited to clinical and drug cost-effectiveness, health care resource utilization, and subject adherence.

03

Conditions studied

  • Generalized Pustular Psoriasis

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04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Subjects are enrolled in the GPP Registry during regularly scheduled office visits. Selected dermatologists are invited to participate as investigators in the Registry.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • A subject must meet all the following criteria to participate in the registry:

    1. Has been diagnosed with GPP by a dermatologist or a qualified dermatology practitioner.
    2. Is at least 18 years of age and has attained the legal age for consent to procedures involved in the research, under the applicable law of the jurisdiction in which the research is being conducted.
    3. Is willing to provide consent for participation in the registry.
    4. Is willing to provide Personal Information

Exclusion criteria

Exclusion Criteria:

  • Any of the following would exclude the subject from participating in the registry:

    1. Is participating or planning to participate in a blinded clinical trial evaluating a systemic agent for the treatment or prevention of flares related to GPP.
    2. Is enrolled in another CorEvitas registry for a dermatological condition. Subjects enrolled in another CorEvitas registry must be exited to be eligible for enrollment into the GPP Registry
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
46 participants (actual)
Patient registry
No

Groups and cohorts

  • Generalized Pustular Psoriasis (GPP)

    Pts presenting to enrolling sites across the North America are invited to enroll if eligible

06

What researchers measure

Primary outcomes

  1. Primary Outcome Measure:GPP epidemiology and Presentation

    The major clinical outcomes include an assessment of the epidemiology of GPP; to better understand the presentation and natural history.

    Time frame: Through study completion, an average of 10 years

  2. GPP management, and outcomes

    The major clinical outcome include an assessment of the epidemiology of GPP; to better understand the management and outcomes.

    Time frame: Through study completion, an average of 10 years

07

Study locations

1 site
08

References and documents

Related links

Individual participant data

Plan to share: No

09

Timeline

2 registry updates since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedDate before it movedWhere the date was before it movedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Sep 2023 to primary completion in Nov 2026, 37 months.

Of 92 non-industry observational studies under Psoriasis, half reached primary completion within 43 months of starting (the median), counting those still running; a quarter within 17 and three quarters within 119. This study's 37 months is below that.

Counting every sponsor, half of 173 studies reached it within 37 months; a quarter within 23 and three quarters within 93.

Since we started tracking on Sep 25, 2026, the dates moved once, on Nov 6, 2026: primary completion Dec 2099 → Nov 2026 and completion Dec 2099 → Nov 2026.

Earlier changes are on the record history on ClinicalTrials.gov ↗

How these figures are worked out, and which studies are left out of them.

Registered
Oct 3, 2023
First posted
Oct 25, 2023
StartActual
Sep 19, 2023
Primary completionActual
Nov 1, 2026was Dec 2099
CompletionActual
Nov 1, 2026was Dec 2099
Last update
Nov 6, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Status
Recruiting→Active, not recruiting→Completed
changed Oct 22, 2026 · changed Nov 6, 2026
Primary completion
Dec 2099→Nov 1, 2026 (actual)
Nov 6, 2026
Study completion
Dec 2099→Nov 1, 2026 (actual)
Nov 6, 2026
Enrollment
200 (estimated)→46 (actual)
Nov 6, 2026
Show all 2 updates
  1. Nov 6, 2026
    Active, not recruiting→Completed
    Primary completion Dec 2099→Nov 1, 2026 (now actual)
    Study completion Dec 2099→Nov 1, 2026 (now actual)
    Enrollment 200 (estimated)→46 (actual)
  2. Oct 22, 2026
    Recruiting→Active, not recruiting
    + 3 other changes: verification date, contact details and site details

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT06100991
Lead sponsor
CorEvitas
Responsible party
Sponsor
First posted
Oct 25, 2023
Start date
Sep 19, 2023
Primary completion
Nov 1, 2026
Completion
Nov 1, 2026
Last update
Nov 6, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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