ClinicalTrials.gg
RecruitingNCT07489885N/ZUpdated Jul 9, 2026

A Study to Evaluate D-2570 in Participants With Moderate to Severe Plaque Psoriasis

A Phase 2 interventional study of D-2570 Tablet and Placebo Tablets in Psoriasis, sponsored by InventisBio Co., Ltd. Recruiting at 20 sites in United States. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-07-09.

Sponsored by InventisBio Co., Ltd · Phase 2, Interventional, and Treatment

From the registry’s dates

  • Started Jun 2026; still recruiting 5 months later.
Phase
Phase 2
Study type
Interventional
Enrollment
75
Allocation
Randomized
Ages
18 Years to 70 Years
Sex
All
01

Study summary

A Study looking at the safety and efficacy of D-2570 in Participants with Plaque Psoriasis

Read the detailed description

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Study to Evaluate the Efficacy and Safety of D-2570 in Participants with Moderate to Severe Plaque Psoriasis

02

Conditions studied

  • Psoriasis

Browse trials for

Keywords

  • Moderate to Severe Plaque Psoriasis
03

In context

Psoriasis

2,028 studies on the registry are indexed under Psoriasis; 275 are open to participants now.

This study's planned enrollment of 75 is close to the median of 75 across 1,565 interventional studies indexed under Psoriasis.

Browse Psoriasis studies →

Lead sponsor

InventisBio Co., Ltd is the lead sponsor of 34 studies on the registry; 11 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Participants with a diagnosis of plaque psoriasis with no significant flares of disease activity for at least 6 months before signing the
  • Participants have moderate to severe plaque psoriasis as defined by a total body surface area (BSA) ≥10%, a Psoriasis Area and Severity Index (PASI) score ≥ 12 and a Physician's Global Assessment (PGA) score ≥ 3.
  • Within normal ranges of laboratory assessments

Exclusion criteria

Exclusion Criteria:

  • Any comorbidities or past medical conditions as outlined in the protocol that would interfere with study assessments as deemed by the Investigator
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
75 participants (estimated)

Study arms

  • Active comparator
    D-2570 low dose

    Low dose of D-2570

    Drug: D-2570 Tablet

  • Active comparator
    D-2570 High Dose

    medium dose level of D-2570

    Drug: D-2570 Tablet

  • Placebo comparator
    Placebo

    Placebo arm

    Drug: Placebo Tablets

Interventions

  • Active Treatment

  • DrugPlacebo Tablets

    Identical Tablet

06

What researchers measure

Primary outcomes

  1. Improvement in PASI-90

    Proportion of participants achieving at least a 90% improvement from baseline in Psoriasis Area and Severity Index (PASI-90) at Week 12

    Time frame: Assessment completed after 12 weeks of treatment/placebo

07

Study locations

3 of 20 sites recruiting
  • Study Center
    Birmingham, Alabama 35244, United States
    Recruiting
  • Study Center
    Phoenix, Arizona 85008, United States
    Not yet recruiting
  • Study Center
    Chula Vista, California 91910, United States
    Recruiting
  • Study Center
    Fountain Valley, California 92708, United States
    Not yet recruiting
  • Study Center
    Fremont, California 94538, United States
    Not yet recruiting
  • Study Center
    Los Angeles, California 90017, United States
    Not yet recruiting
  • Study Center
    Los Angeles, California 90024, United States
    Not yet recruiting
  • Study Center
    San Diego, California 92123, United States
    Not yet recruiting
  • Study Center
    Fort Lauderdale, Florida 33308, United States
    Not yet recruiting
  • Study Center
    Miramar, Florida 33027, United States
    Not yet recruiting
  • Study Center
    Ocala, Florida 34470, United States
    Not yet recruiting
  • Study Center
    Tampa, Florida 33607, United States
    Not yet recruiting
  • Study Center
    Sandy Springs, Georgia 30328, United States
    Not yet recruiting
  • Study Center
    Savannah, Georgia 31419, United States
    Not yet recruiting
  • Study Center
    Idaho Falls, Idaho 83404, United States
    Not yet recruiting
  • Study Center
    Clarksville, Indiana 40241, United States
    Not yet recruiting
  • Study Center
    Louisville, Kentucky 40241, United States
    Not yet recruiting
  • Study Center
    Mayfield Heights, Ohio 44124, United States
    Not yet recruiting
  • Study Center
    Philadelphia, Pennsylvania 19103, United States
    Not yet recruiting
  • Study Center
    San Antonio, Texas 78218, United States
    Recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 9, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07489885
Responsible party
Sponsor
First posted
Mar 24, 2026
Start date
Jun 3, 2026
Primary completion
Aug 2027 (estimated)
Completion
Dec 2027 (estimated)
Last update
Jul 9, 2026

Study contacts

Kathryn Stazzone
Contact
kathryn.stazzone@inventisbio.com
3025195966

Oversight

Data monitoring committee
No
FDA-regulated drug
Yes
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Studies of the drug tested here: D-2570

Start the discussion