A Phase 4 interventional study of 0.9% Sodium chloride and 95% ethanol in Osteo Arthritis Knee and Osteoarthritis, sponsored by Poznan University of Medical Sciences. Completed at 1 site in Poland. Open to participants aged 18 Years to 110 Years. Per ClinicalTrials.gov, last updated 2025-01-21.
Sponsored by Poznan University of Medical Sciences · Phase 4, Interventional, and Treatment
Genicular nerves chemical neurolysis in advanced osteoarthritis of the knee joint.
The study aims to assess the safety and effectiveness of regional pain treatment methods and their impact on the quality of life of patients with advanced osteoarthritis of the knee joint.
4,399 studies on the registry are indexed under Osteoarthritis; 583 are open to participants now.
This study's enrollment of 100 is above the median of 70 across 3,440 interventional studies indexed under Osteoarthritis.
Browse Osteoarthritis studies →Poznan University of Medical Sciences is the lead sponsor of 143 studies on the registry; 46 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
US-guided Bilateral genicular nerve block with 0,9% NaCl
Drug: 0.9% Sodium chloride
US-guided Bilateral genicular nerve neurolysis with 0,5ml 95% ethanol
Drug: 95% ethanol
us-guided bilateral genicular nerves sham block with 0,5ml 0,9% normal saline
Also known as: Sham block
us-guided bilateral genicular nerves neurolysis with 0,5ml 95% ethanol
Also known as: neurolisis
NRS
The numeric rating scale (NRS) is a pain screening tool, commonly used to assess pain severity at that moment in time using a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable"
Time frame: 7 days after procedure
NRS
The numeric rating scale (NRS) is a pain screening tool, commonly used to assess pain severity at that moment in time using a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable"
Time frame: 30 days after procedure
NRS
The numeric rating scale (NRS) is a pain screening tool, commonly used to assess pain severity at that moment in time using a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable"
Time frame: 3 months after procedure
NRS
The numeric rating scale (NRS) is a pain screening tool, commonly used to assess pain severity at that moment in time using a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable"
Time frame: 6 months after procedure
Health Questionnaire (EQ-5D-5L)
The descriptive system comprises five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and extreme problems. The patient is asked to indicate his/her health state by ticking the box next to the most appropriate statement in each of the five dimensions. This decision results in a 1-digit number that expresses the level selected for that dimension. The digits for the five dimensions can be combined into a 5-digit number that describes the patient's health state.
Time frame: 7 days after surgery
Health Questionnaire (EQ-5D-5L)
The descriptive system comprises five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and extreme problems. The patient is asked to indicate his/her health state by ticking the box next to the most appropriate statement in each of the five dimensions. This decision results in a 1-digit number that expresses the level selected for that dimension. The digits for the five dimensions can be combined into a 5-digit number that describes the patient's health state.
Time frame: 30 days after surgery
Health Questionnaire (EQ-5D-5L)
The descriptive system comprises five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and extreme problems. The patient is asked to indicate his/her health state by ticking the box next to the most appropriate statement in each of the five dimensions. This decision results in a 1-digit number that expresses the level selected for that dimension. The digits for the five dimensions can be combined into a 5-digit number that describes the patient's health state.
Time frame: 3 months after surgery
Health Questionnaire (EQ-5D-5L)
The descriptive system comprises five dimensions: mobility, self-care, usual activities, pain/discomfort and anxiety/depression. Each dimension has 5 levels: no problems, slight problems, moderate problems, severe problems and extreme problems. The patient is asked to indicate his/her health state by ticking the box next to the most appropriate statement in each of the five dimensions. This decision results in a 1-digit number that expresses the level selected for that dimension. The digits for the five dimensions can be combined into a 5-digit number that describes the patient's health state.
Time frame: 6 months after surgery
neurological deficits
yes/no
Time frame: 7 days after procedures
neurological deficits
yes/no
Time frame: 30 days after procedures
neurological deficits
yes/no
Time frame: 3 months after procedures
neurological deficits
yes/no
Time frame: 6 months after procedures
total opioid consumption
milligrams of oral morphine per day
Time frame: 7 days after procedure
total opioid consumption
milligrams of oral morphine per day
Time frame: 30 days after procedure
total opioid consumption
milligrams of oral morphine per day
Time frame: 3 months after procedure
total opioid consumption
milligrams of oral morphine per day
Time frame: 6 months after procedure
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.
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Poznan University of Medical Sciences