An interventional study of Flavonoids in Long Covid19 and Fatigue Syndrome, Chronic, sponsored by Guillermo Ceballos Reyes. Completed at 1 site in Mexico. Open to participants aged 30 Years to 70 Years. Per ClinicalTrials.gov, last updated 2024-10-01.
Sponsored by Guillermo Ceballos Reyes · Not applicable, Interventional, and Treatment
The study use a triple blind, placebo-controlled design enrolling male and female subjects between 30-70 yo to evaluate the effect of daily consumption of a cacao supplement on inflammation, endothelial damage, handgrip strength, fatigue scale and quality of life.
The study use a triple blind, placebo-controlled design enrolling male and female subjects between 30-70 yo distributed homogeneously at random in two groups: the control group (Placebo) and the intervention group (Cacao Flavonoids) both groups affected for 90 days.
The variables to consider will be: Interleukins (IL-1b, IL-6), Tumoral Necrosis Factor alpha (TNF-α) and syndecan-1.
For physical performance is evaluated the handgrip strength. The investigators also assessed quality of life using the Health Related QoL (EQ-5D) questionnaire, and the numerical fatigue rating scale.
7,640 studies on the registry are indexed under COVID-19; 488 are open to participants now.
This study's enrollment of 46 is below the median of 100 across 4,099 interventional studies indexed under COVID-19.
Browse COVID-19 studies →This is the only study on the registry with Guillermo Ceballos Reyes as lead sponsor.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Capsules with 500mg of cacao flavonoids, twice a day for 90 days
Dietary Supplement: Flavonoids
Capsules with 500mg of excipients, twice a day for 90 days
Dietary Supplement: Flavonoids
1 capsule every 12h for 90 days
Also known as: Cacao and Health EC-Fitness
Interleukin-1b
Plasmatic concentration
Time frame: At 0 and 90 day
Interleukin-6
Plasmatic concentration
Time frame: At 0 and 90 day
TNF-alpha
Plasmatic concentration
Time frame: At 0 and 90 day
Syndecan-1
Plasmatic concentration
Time frame: At 0 and 90 day
EQ-5D questionnaire
Self-administered health index that explores five domains
Time frame: At 0 and 90 day
Analog Visual Scale
Use of a Analog Visual Scale to measure the quality of life, graded 0 (worst) to 100 (best) for the perception of wellbeing.
Time frame: At 0 and 90 day
Numerical fatigue rating scale
fatigue rating scale graded 0 (best) to 100 (worst)
Time frame: At 0 and 90 day
Handgrip strength
Measures static force in kilograms that the hand can squeeze around a dynamometer
Time frame: At 0 and 90 day
This study is completed, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.
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