An observational study in Complex Regional Pain Syndromes, sponsored by Seoul National University. Recruiting at 1 site in Korea, Republic of. Open to participants aged 19 Years to 80 Years. Per ClinicalTrials.gov, last updated 2024-05-29.
Sponsored by Seoul National University · Observational
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This observational study aims to understand phenotype-specific molecular signatures in patients with complex regional pain syndrome (CRPS).
Participants who meet the diagnostic criteria for CRPS, aged 19\~80 years, and agree to participate in this study will undergo a 4mm-sized skin punch biopsy in the involved limb, as well as the contralateral side (internal control).
Spatial transcriptomics will be used to identify immune cell signatures and differentially regulated genes (DEGs) in the epidermis, vasculature, sweat gland, and nerve plexus of the involved ipsilateral (vs contralateral) side of the patient's skin.
206 studies on the registry are indexed under Complex Regional Pain Syndromes; 55 are open to participants now.
This study's planned enrollment of 10 is below the median of 58 across 44 observational studies indexed under Complex Regional Pain Syndromes.
Browse Complex Regional Pain Syndromes studies →Seoul National University is the lead sponsor of 32 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with CRPS
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
A biopsy takes a small piece of tissue to examine. “Archival tissue” is a sample already taken, for example at diagnosis, and kept by the hospital.
Whether a stored sample will do depends on when it was taken, how much there is and what the study needs. Ask whether the study accepts your stored sample or needs a new biopsy.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Biopsy and archival tissue
A biopsy takes a small piece of tissue to examine. “Archival tissue” is a sample already taken, for example at diagnosis, and kept by the hospital.
Whether a stored sample will do depends on when it was taken, how much there is and what the study needs. Ask whether the study accepts your stored sample or needs a new biopsy.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Numerical Rating Scale (NRS)
Intensity of pain (now, weekly avarege, weekly maximum)
Time frame: At the time of biopsy
Thermography
Thermography of the involved limb
Time frame: At the time of diagnosis
Quantitative Sensory Testing (QST)
Vibration Detection Threshold (VDT), Cold Detection Threshold (CDT)
Time frame: At the time of diagnosis
Plan to share: No
Started Jul 2023 (actual). Primary completion is estimated for Dec 2024, 17 months after the start.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Complex Regional Pain Syndromes →
Seoul National University