A Phase 1 interventional study of 5%potassium hydroxide and Liquid nitrogen in Plan Warts, sponsored by Combined Military Hospital Abbottabad. Completed at 1 site in Pakistan. Open to participants aged 4 Years to 30 Years. Per ClinicalTrials.gov, last updated 2023-06-08.
Sponsored by Combined Military Hospital Abbottabad · Phase 1, Interventional, and Treatment
ABSTRACT Objective: To study the efficacy while comparing Potassium hydroxide 5% with liquid nitrogen in treatment of plane warts.
Study design: Randomized-controlled trial (RCT), (Double-blind). Study setting and duration: Dept dermatology, CMH-Abbottabad, Nov-2022 / April-2023.
Methodology: The sample size of 60 patients (children and adults aged 4 to 30 years) was calculated using Openepi app sample size RCT calculator, after informed consent by using non-probability consecutive sampling technique. Patients randomly assigned into two groups i.e. In group-A 30 patients were given topical 5%-potassium hydroxide solution on affected area once at night upto 4 weeks and in group-B 30 patients treated with cotton bud method of cryotherapy with liquid nitrogen once every two weeks. Patients were reassessed at every two weeks and final assessment was done at 12th week whereas followed up for 3 months to monitor recurrence. Demographic information and frequency percentages were calculated for qualitative variables by using SPSS26. To determine statistical significance taking p-value \<0.05 as significant, and χ2-square test was used.
171 studies on the registry are indexed under Warts; 35 are open to participants now.
This study's enrollment of 60 is below the median of 70 across 155 interventional studies indexed under Warts.
Browse Warts studies →Combined Military Hospital Abbottabad is the lead sponsor of 25 studies on the registry; 3 are open to participants now.
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In group-A 30 patients were given topical 5%-potassium hydroxide solution on affected area once at night upto 4 weeks
Drug: 5%potassium hydroxide
in group-B 30 patients treated with cotton bud method of cryotherapy with liquid nitrogen once every two weeks. Patients were reassessed at every two weeks and final assessment was done at 12th week.
Drug: Liquid nitrogen
. In group-A 30 patients were given topical 5% potassium hydroxide solution on affected area once at night for upto 4 weeks
in group-B 30 patients treated with cotton bud method of cryotherapy with liquid nitrogen once every two weeks. Patients were reassessed at every two weeks. The treatment carried out upto 12 weeks or until complete recovery from warts.
Comparative Efficacy of topical 5% Potassium hydroxide and liquid nitrogen in the treatment of plane warts
Decrease in number or size of warts
Time frame: 12 weeks
This study is completed, as verified in May 2023. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Nitrogen, liquid
Combined Military Hospital Abbottabad