An observational study in Trauma Injury, Trauma and Open Fracture, sponsored by Dartmouth-Hitchcock Medical Center. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-02.
Sponsored by Dartmouth-Hitchcock Medical Center · Observational
This is a pilot prospective, observational study of patients with open or infected fracture evaluating the feasibility and acceptability of OCT, a light-based imaging modality that requires no drug or contrast agent.
128 studies on the registry are indexed under Accidental Injuries; 39 are open to participants now.
This study's planned enrollment of 40 is below the median of 170 across 59 observational studies indexed under Accidental Injuries.
Browse Accidental Injuries studies →Dartmouth-Hitchcock Medical Center is the lead sponsor of 488 studies on the registry; 71 are open to participants now.
Of its 31 completed or terminated interventional studies of FDA-regulated products, 21 (68%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients 18 years of age or older who present to DHMC (Lebanon) with open and infected fracture
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
High energy open fracture.
Procedure: Open Fracture
Infected open or closed fracture.
Procedure: Infected Fracture
Patients 18 years of age or older with open fracture. Provision of informed consent.
Patients 18 years of age or older with infected fracture. Provision of informed consent.
Feasibility and acceptability of OCT imaging
The primary objective of this work is to demonstrate feasibility, acceptability, and preliminary effectiveness of Optical Coherence Tomography (OCT) to image bacteria and biofilm. Data will be analyzed accordingly: The association between optical imaging parameters (particularly around biofilm and bacterial contamination) and (1) surgical wound severity and (2) development of infection or treatment failure for infection.
Time frame: 36 months
Ran from Mar 2023 to primary completion in Jul 2026, 40 months.
Of 33 non-industry observational studies under Accidental Injuries, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 60. This study's 40 months is above that.
Counting every sponsor, half of 39 studies reached it within 31 months; a quarter within 12 and three quarters within 60.
Primary completion moved once since we started tracking on Sep 25, 2026: Aug 2026 → Jul 2026, on Oct 2, 2026.
Earlier changes are on the record history on ClinicalTrials.gov ↗
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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Dartmouth-Hitchcock Medical Center →