An interventional study of PRP and Normal Saline in Osteoarthritis, Knee, sponsored by Universitas Bali Internasional. Completed at 1 site in Indonesia. Open to participants aged 40 Years to 80 Years. Per ClinicalTrials.gov, last updated 2023-02-10.
Sponsored by Universitas Bali Internasional · Not applicable, Interventional, and Treatment
This is a single-center, randomized control trial The aim of this study is to compare PRP with placebo as the treatment of knee OA Conducted at Puri Raharja Hospital Bali in January-June 2022 Sample consisted of 106 patients with knee OA grades 2-3 Kellgren-Lawrence, randomized into PRP group and placebo group Samples were injected with 2 ml PRP or normal saline twice at one-week interval The severity of knee OA was assessed by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) before injection and two weeks after the first injection.
4,398 studies on the registry are indexed under Osteoarthritis; 582 are open to participants now.
This study's enrollment of 106 is above the median of 70 across 3,440 interventional studies indexed under Osteoarthritis.
Browse Osteoarthritis studies →This is the only study on the registry with Universitas Bali Internasional as lead sponsor.
Counted across the registry records on this site, refreshed daily.
patients with knee pain for at least three months, aged between 40 to 80 years old, and whose results of radiological examination of the knee indicated OA grades 2-4 based on the Kellgren Lawrence classification
Exclusion Criteria:
polyarticular rheumatic disease; knee arthroscopy \<1 year; intra-articular injection of hyaluronic acid (HA) or steroids in the past three months; current infection, diabetes, rheumatoid arthritis, coagulopathy disorders, anticoagulant or antiplatelet aggregation therapy, immunodeficiency disease, taking non-steroidal anti-inflammatory drugs (NSAIDs) two weeks prior to the procedure, knee trauma; inflammation; and tumors around the knee
PRP manufactured by T_Biyoteknoloji LTD, Turkey
Procedure: PRP
NaCl 0.9%
Other: Normal Saline
2 ml of platelet rich plasma intraarticular injection twice in one week interval
Also known as: T_Biyoteknoloji LTD, Turkey
NaCl 0.9%
Also known as: NaCl 0.9%
WOMAC
The Western Ontario and McMaster Universities Arthritis Index (WOMAC) based on questionnaire
Time frame: 2 weeks
Plan to share: No
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This study is completed, as verified in Feb 2023. You cannot join it, but the record below documents what was studied.
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