An observational study in Parkinson's Disease, Perception and Visual Hallucination, sponsored by Boston University Charles River Campus. Completed at 1 site in United States. Open to participants aged 40 Years to 110 Years. Per ClinicalTrials.gov, last updated 2025-09-19.
Sponsored by Boston University Charles River Campus · Observational
The investigators plan to examine the relation of perceptual variables-basic vision, unusual perceptual experiences(including but not limited to visual hallucinations)-to relevant functional variables such as cognition, mood, and alertness/sleepiness in an online sample of persons with Parkinson's disease (PwPD). It is hypothesized that unusual perceptual experiences will relate significantly to the selected variables. Participants do not need to experience visual hallucinations to be able to participate in this study. This is an observational study only, and not an interventional study.
For this study, the investigators propose to conduct an online study of PwPD (proposing a total of 60 participants) to examine the relations among variables that may relate to perception in PD. Those PwPD who express interest will be sent a link to an online survey (Qualtrics). The investigators will collect demographic and health information, followed by questionnaires assessing unusual perceptual experiences, mood, motivation, sleep, fatigue and quality of life. The survey should take roughly 45 minutes to an hour to complete.
Compensation: A $20 Amazon gift card will be offered to those who complete the survey all the way through with good effort.
4,573 studies on the registry are indexed under Parkinson Disease; 1,086 are open to participants now.
This study's enrollment of 54 is below the median of 96 across 1,085 observational studies indexed under Parkinson Disease.
Browse Parkinson Disease studies →Boston University Charles River Campus is the lead sponsor of 159 studies on the registry; 33 are open to participants now.
Of its 14 completed or terminated interventional studies of FDA-regulated products, 9 (64%) have results posted.
Counted across the registry records on this site, refreshed daily.
PwPD volunteering for an online study
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Noise Pareidolia Test
Assesses tendency to see meaningful objects such as faces, animals, and objects in ambiguous patterns. Higher scores (on items with no face) indicate a higher number of pareidolic responses.
Time frame: Baseline
Mooney Faces
Assesses the ability to see an upright, inverted, or scrambled face in a black and white pattern. Higher scores (on items with no face) indicate a higher number of pareidolic responses.
Time frame: Baseline
BU Hallucinations and Unusual Perceptual Experiences questionnaire (BU-HUPE)
Assesses different types of visual hallucinations - simple VH; illusions; minor hallucinations: vivid sense of presence or movement in periphery (passage); and complex VH (e.g., people, animals, objects), as well as temporal and descriptive characteristics of the hallucinations. Higher scores indicate more unusual perceptual experiences.
Time frame: Baseline
Prodromal Questionnaire, Brief Version (PQ-B)
Assesses risk for psychosis by asking about positive symptoms and related distress/impairment. Higher scores indicate higher risk for psychosis and higher related distress.
Time frame: Baseline
Parkinson's Disease - Psychotic Symptoms Scale (PD-PSS)
Assesses the frequency and severity of minor hallucinations (passage hallucinations, presence hallucinations, visual illusions), and structured hallucinations in PD. Higher scores indicate higher frequency of psychotic symptoms.
Time frame: Baseline
Penn Online Evaluation of Migraine (POEM)
Assesses headaches and migraine-related history.
Time frame: Baseline
Epworth Sleepiness Scale (ESS)
Assesses a person's general level of daytime sleepiness. Maximum Score: 24. Higher scores indicate a higher chance of dozing.
Time frame: Baseline
Parkinson's Disease Sleep Scale-2
Assesses sleep and nocturnal disturbances in Parkinson's disease. Maximum score: 60. Higher scores indicate more frequent sleep disturbances.
Time frame: Baseline
Parkinson's Anxiety Scale (PAS)
Assesses the severity of anxiety symptoms in persons with Parkinson's disease. Maximum score:48. Higher scores indicate more severe anxiety.
Time frame: Baseline
Center for Epidemiological Studies Depression Scale (CES-D)
Assesses depressive symptoms in the general population. Maximum score:60. Higher scores indicate more severe depression.
Time frame: Baseline
Parkinson's Disease Questionnaire - 39 (PDQ-39)
Assesses Parkinson's disease-specific health-related quality of life. Higher scores indicate worse quality of life.
Time frame: Baseline
NIH NeuroQoL measures
Assesses health-related quality of life in adults with neurological disorders. Higher scores on the sub-scales indicate worse outcomes.
Time frame: Baseline
The Movement Disorders Society Unified Parkinson Disease Rating Scale (MDS-UPDRS)
Assesses motor and non-motor experiences of daily living in Parkinson's disease. Higher scores indicate increased severity of motor and non-motor symptoms.
Time frame: Baseline
Non-Motor Symptoms Questionnaire (NMSQ)
Assesses a range of non-motor symptoms in Parkinson's disease. Higher scores indicate the presence of more non-motor symptoms.
Time frame: Baseline
Plan to share: No
This study is completed, as verified in Aug 2024. You cannot join it, but the record below documents what was studied.
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